[HTML][HTML] The role of RNA-binding proteins in the processing of mRNAs produced by carcinogenic papillomaviruses

N Kajitani, S Schwartz - Seminars in Cancer Biology, 2022 - Elsevier
Human papillomaviruses (HPV) are epitheliotropic DNA tumor viruses that are prevalent in
the human population. A subset of the HPVs termed high-risk HPVs (HR-HPVs) are …

The role of E6 spliced isoforms (E6*) in human papillomavirus-induced carcinogenesis

L Olmedo-Nieva, JO Muñoz-Bello… - Viruses, 2018 - mdpi.com
Persistent infections with High Risk Human Papillomaviruses (HR-HPVs) are the main
cause of cervical cancer development. The E6 and E7 oncoproteins of HR-HPVs are derived …

Long-read sequencing reveals oncogenic mechanism of HPV-human fusion transcripts in cervical cancer

M Liu, Z Han, Y Zhi, Y Ruan, G Cao, G Wang, X Xu… - Translational …, 2023 - Elsevier
Integration of high-risk human papillomavirus (HPV) into the host genome is a crucial event
for the development of cervical cancer, however, the underlying mechanism of HPV …

miR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3ζ

HM Jung, BL Phillips, EKL Chan - Molecular cancer, 2014 - Springer
Abstract Background While microRNAs (miRNAs) are extensively studied in post-
transcriptional regulation of gene expressions in many biological processes, cellular miRNA …

Alternative splicing in the genome of HPV and its regulation

Y Wang, F Chen, W Qu, Y Gong, Y Wang… - Frontiers in Cellular …, 2024 - frontiersin.org
Persistent infection with high-risk human papillomavirus (HR-HPV) is the main cause of
cervical cancer. These chronic infections are characterized by high expression of the HPV …

[HTML][HTML] Changes in global gene expression profiles induced by HPV 16 E6 oncoprotein variants in cervical carcinoma C33-A cells

AE Zacapala-Gómez, O Del Moral-Hernández… - Virology, 2016 - Elsevier
We analyzed the effects of the expression of HPV 16 E6 oncoprotein variants (AA-a, AA-c, E-
A176/G350, E-C188/G350, E-G350), and the E-Prototype in global gene expression profiles …

Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) and hnRNP A2 inhibit splicing to human papillomavirus 16 splice site SA409 through a UAG-containing …

Y Zheng, J Jönsson, C Hao… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT Human papillomavirus 16 (HPV16) 5′-splice site SD226 and 3′-splice site
SA409 are required for production of the HPV16 E7 mRNAs, whereas unspliced mRNAs …

Codon usage roles in human papillomavirus

KN Zhao, J Chen - Reviews in medical virology, 2011 - Wiley Online Library
Human papillomavirus (HPV) genomes, similar to other virus genomes, frequently have a
G+ C content significantly different from their host species. The HPV genomes show a strong …

Comparative RNA sequencing reveals that HPV16 E6 abrogates the effect of E6* I on ROS metabolism

P Paget-Bailly, K Meznad, D Bruyère, J Perrard… - Scientific reports, 2019 - nature.com
Abstract High-risk Human Papillomavirus infections are responsible for anogenital and
oropharyngeal cancers. Alternative splicing is an important mechanism controlling HPV16 …

Two less common human microRNAs miR-875 and miR-3144 target a conserved site of E6 oncogene in most high-risk human papillomavirus subtypes

L Lin, Q Cai, X Zhang, H Zhang, Y Zhong, C Xu… - Protein & …, 2015 - academic.oup.com
Human papillomaviruses (HPVs) including high-risk (HR) and low-risk (LR) subtypes have
distinguishable variation on both genotypes and phenotypes. The co-infection of multiple …