Glioblastoma multiforme is the most aggressive malignant tumor of the central nervous
system. Due to the absence of effective pharmacological and surgical treatments, the …

Different immunotherapeutic approaches have proved to be of significant clinical value to
many patients with different types of advanced cancer. However, we need more precise …

Oral squamous cell carcinoma (OSCC) is the leading cause of mortality for oral cancer.
Numerous risk factors mainly related to unhealthy habits and responsible for chronic …

The extracellular matrix (ECM) plays an important role in the regulation of the tissue
microenvironment and in the maintenance of cellular homeostasis. Several proteins with a …

Colorectal cancer (CRC) is one of the leading cause of cancer death worldwide. Currently,
no effective early diagnostic biomarkers are available for colorectal carcinoma. Therefore …

Ageing is the major risk factor for cancer development. Hallmark of the ageing process is
represented by inflammaging, which is a chronic and systemic low-grade inflammatory …

Background: Oral cancer is one of the most prevalent cancers worldwide. Despite that the
oral cavity is easily accessible for clinical examinations, oral cancers are often not promptly …

Activated microglia cells (MCs) are able to release a large amount of inflammatory cytokines
after ischemic stroke, which exacerbates neuron damage. In this study, we explored the …

Simple Summary Healthy diet and physical activity are able to induce beneficial molecular
modifications that have been associated with a lower risk of breast cancer (BC) incidence …

Matrix metalloproteinases (MMPs) or matrixins, are members of a zinc-dependent
endopeptidase family. They cause remodeling of the extracellular matrix (ECM) leading to …