Astrocytes functionally interact with neurons and with other brain cells. Although not
electrically excitable, astrocytes display a complex repertoire of intracellular Ca2+ signalling …

Glia play a crucial role in providing metabolic support to neurons across different species. To
do so, glial cells isolate distinct neuronal compartments from systemic signals and …

Thirst emerges from a range of cellular changes that ultimately motivate an animal to
consume water. Although thirst-responsive neuronal signals have been reported, the full …

Highlights•Drosophila glia share many properties with their mammalian
counterparts.•Different subpopulations of glia cells cooperate to support neuronal energy …

Metal homeostasis is critical to normal neurophysiological activity. Metal ions are involved in
the development, metabolism, redox and neurotransmitter transmission of the central …

Spontaneous Ca2+ transients of neural cells is a hallmark of the developing nervous
system. It is widely accepted that chemical signals, like neurotransmitters, contribute to …

Astrocytes are active cells involved in brain function through the bidirectional communication
with neurons, in which astrocyte calcium plays a crucial role. Synaptically evoked calcium …

Molecular genetic approaches in small model organisms like Drosophila have helped to
elucidate fundamental principles of neuronal cell biology. Much less is understood about …

Folates are B-group vitamins that function in one-carbon metabolism. Here we show that a
specific folate can activate serotonergic neurons in C. elegans to modulate behavior through …

The Drosophila nervous system comprises a small number of well characterized glial cell
classes. The outer surface of the central nervous system (CNS) is protected by a glial …