Selenium is an essential microelement required for a number of biological functions.
Selenium—and more specifically the amino acid selenocysteine—is present in at least 25 …

Treatments for Alzheimer's disease (AD) directed against the prominent amyloid plaque
neuropathology are yet to be proved effective despite many phase 3 clinical trials. There are …

Alzheimer's Disease (AD) is a progressive neurodegenerative disease characterized by
amyloid-β (Aβ) plaque deposition and neurofibrillary tangle accumulation in the brain …

Alterations in the concentrations of trace elements may play a vital role in Alzheimer
dementia progression. However, previous research results are inconsistent, and there is still …

Since its inception in the early 80s, inductively coupled plasma–mass spectrometry has
developed to the method of choice for the analysis of elements in complex biological …

The thioredoxin system, consisting of thioredoxin (Trx), thioredoxin reductase (TrxR), and
NADPH, plays a fundamental role in the control of antioxidant defenses, cell proliferation …

The role of metals in the pathogenesis of Alzheimer's disease (AD) is still debated. Although
previous research has linked changes in essential metal homeostasis and exposure to …

Background: The association of zinc, iron, copper, and selenium intakes with cognitive
function is poorly understood so far. Objective: To examine the associations of dietary and …

Various metals have been associated with the pathogenesis of Alzheimer's disease (AD),
principally heavy metals that are environmental pollutants (such as As, Cd, Hg, and Pb) and …

Oxidative damage is involved in the pathophysiology of age-related ailments, including
Alzheimer's disease (AD). Studies have shown that the brain tissue and also lymphocytes …