A review of genome‐wide transcriptomics studies in Parkinson's disease

G Borrageiro, W Haylett, S Seedat… - European Journal of …, 2018 - Wiley Online Library
Parkinson's disease (PD) is a progressive and incurable neurodegenerative disorder.
Although numerous genetic and environmental factors have been linked to the aetiology of …

Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Parkinson's disease

OA Mohammed, MS Elballal, AA El-Husseiny… - … -Research and Practice, 2024 - Elsevier
Parkinson's disease (PD) is a debilitating neurological disorder characterized by the
impairment of the motor system, resulting in symptoms such as resting tremor, cogwheel …

The role of non-coding RNAs in the pathogenesis of Parkinson's disease: recent advancement

H Zhang, L Yao, Z Zheng, S Koc, G Lu - Pharmaceuticals, 2022 - mdpi.com
Parkinson's disease (PD) is a prevalent neurodegenerative aging disorder that manifests as
motor and non-motor symptoms, and its etiopathogenesis is influenced by non-coding RNAs …

MicroRNA alterations in iPSC-derived dopaminergic neurons from Parkinson disease patients

E Tolosa, T Botta-Orfila, X Morató, C Calatayud… - Neurobiology of …, 2018 - Elsevier
MicroRNA (miRNA) misregulation in peripheral blood has been linked to Parkinson disease
(PD) but its role in the disease progression remains elusive. We performed an explorative …

MiRNA profile in the substantia nigra of Parkinson's disease and healthy subjects

LF Cardo, E Coto, R Ribacoba, M Menéndez… - Journal of Molecular …, 2014 - Springer
The deregulation of several microRNAs (miRNAs) has been associated with
neurodegenerative processes, including Parkinson's disease (PD). Our aim was to …

MicroRNA expressing profiles in A53T mutant alpha-synuclein transgenic mice and Parkinsonian

M Mo, Y Xiao, S Huang, L Cen, X Chen, L Zhang… - …, 2016 - pmc.ncbi.nlm.nih.gov
α-synuclein gene mutations can cause α-synuclein protein aggregation in the midbrain of
Parkinson's disease (PD) patients. MicroRNAs (miRNAs) play a key role in the metabolism …

Construction and analysis of the protein-protein interaction networks based on gene expression profiles of Parkinson's disease

H Rakshit, N Rathi, D Roy - PloS one, 2014 - journals.plos.org
Background Parkinson's Disease (PD) is one of the most prevailing neurodegenerative
diseases. Improving diagnoses and treatments of this disease is essential, as currently there …

Exploring microRNA biomarkers for Parkinson's disease from mRNA expression profiles

YH Taguchi, H Wang - Cells, 2018 - mdpi.com
Parkinson's disease (PD) is a chronic, progressive neurodegenerative disease
characterized by both motor and nonmotor features. The diagnose of PD is based on a …

MiRNA Dysregulation in Brain Injury: An In Silico Study to Clarify the Role of a MiRNA Set

F Sessa, C Pomara, F Schembari… - Current …, 2025 - benthamdirect.com
Background The identification of specific circulating miRNAs has been proposed as a
valuable tool for elucidating the pathophysiology of brain damage or injury and predicting …

Comparative analysis of RNA-Seq data from brain and blood samples of Parkinson's disease

P Chatterjee, D Roy - Biochemical and biophysical research …, 2017 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disorders
throughout the world. In order to search for PD biomarkers, we performed a system-level …