[HTML][HTML] Anal intraepithelial neoplasia: A review of diagnosis and management

JR Roberts, LL Siekas, AM Kaz - World journal of gastrointestinal …, 2017 - ncbi.nlm.nih.gov
Anal intraepithelial neoplasia (AIN) is a premalignant lesion of the anal mucosa that is a
precursor to anal cancer. Although anal cancer is relatively uncommon, rates of this …

Evaluating the efficacy of treatment options for anal intraepithelial neoplasia: a systematic review

DRL Brogden, U Walsh, G Pellino… - International Journal of …, 2021 - Springer
Purpose Anal intraepithelial neoplasia (AIN) is the accepted precursor of anal squamous
cell carcinoma (ASCC). There has long been a hypothesis that treating AIN may prevent …

The American Society of Colon and Rectal Surgeons clinical practice guidelines for anal squamous cell cancers (revised 2018)

DB Stewart, WB Gaertner, SC Glasgow… - Diseases of the Colon …, 2018 - journals.lww.com
The second factor that has resulted in a paradigm shift in understanding the etiology of anal
cancer is the discovery that the human papilloma virus (HPV), especially HPV serotypes 16 …

[HTML][HTML] Anal intraepithelial neoplasia: diagnosis, screening, and treatment

RV Siddharthan, C Lanciault… - Annals of …, 2019 - ncbi.nlm.nih.gov
Anal intraepithelial neoplasia (AIN) is a premalignant lesion for anal cancer. It is more
commonly found in high-risk patients (eg, human papilloma virus (HPV)/human …

Electrocautery ablation of anal high‐grade squamous intraepithelial lesions: effectiveness and key factors associated with outcomes

MM Gaisa, Y Liu, AA Deshmukh, KL Stone, KM Sigel - Cancer, 2020 - Wiley Online Library
Background Electrocautery ablation (EA) is a common treatment modality for patients with
anal high‐grade squamous intraepithelial lesions (HSILs), but to the authors' knowledge its …

Practice parameters for the diagnosis and treatment of anal intraepithelial neoplasia (AIN) on behalf of the Italian Society of Colorectal Surgery (SICCR)

GA Binda, G Gagliardi, I Dal Conte, M Verra… - Techniques in …, 2019 - Springer
Squamous cell carcinoma (SCC) of the anus is a human papilloma virus (HPV) related
malignancy that is preceded by anal intraepithelial neoplasia (AIN) making this cancer, at …

Risk factors of high-grade anal intraepithelial neoplasia recurrence in HIV-infected MSM

J Burgos, A Curran, S Landolfi, A Guelar, L Miguel… - Aids, 2017 - journals.lww.com
Objective: To assess risk factors of high-grade anal intraepithelial neoplasia (HGAIN)
recurrence in a cohort of HIV-infected MSM. Design and methods: Consecutive HIV-infected …

Grading immunohistochemical markers p16INK4a and HPV E4 identifies productive and transforming lesions caused by low‐ and high‐risk HPV within high‐grade …

A Leeman, D Jenkins, E Marra… - British Journal of …, 2020 - academic.oup.com
Objectives Because current guidelines recognise high‐grade anal squamous intraepithelial
lesions (HSILs) and low‐grade SILs (LSILs), and recommend treatment of all HSILs …

Impact of screening and antiretroviral therapy on anal cancer incidence in HIV-positive MSM

N Blaser, B Bertisch, RD Kouyos, A Calmy, HC Bucher… - Aids, 2017 - journals.lww.com
Background: The incidence of anal cancer is high in HIV-positive MSM. We modeled the
impact of screening strategies and combination antiretroviral therapy (cART) coverage on …

Risk factors for≥ high-grade anal intraepithelial lesions in MSM living with HIV and the response to topical and surgical treatments

C Hidalgo-Tenorio, CM García-Martínez, J Pasquau… - PLoS …, 2021 - journals.plos.org
Background The objective of this study in MSM living with HIV was to determine the
incidence of HSIL and ASCC, related factors, and the response to treatment. Patients and …