Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

DNA nanotechnology, in particular DNA origami, enables the bottom-up self-assembly of
micrometre-scale, three-dimensional structures with nanometre-precise features 1, 2, 3, 4, 5 …

In nature, DNA molecules carry the hereditary information. But DNA has physical and
chemical properties that make it attractive for uses beyond heredity. In this Review, we …

Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

It was suggested more than thirty years ago that Watson–Crick base pairing might be used
for the rational design of nanometre-scale structures from nucleic acids. Since then, and …

Abstract The programmability of Watson–Crick base pairing, combined with a decrease in
the cost of synthesis, has made DNA a widely used material for the assembly of molecular …