Mechanisms for soft‐tissue ablation and the development of alternative medical lasers based on investigations with mid‐infrared free‐electron lasers

GS Edwards - Laser & Photonics Reviews, 2009 - Wiley Online Library
Experimental evidence indicating the potential biomedical advantages of using a Mark‐III
Free‐Electron Laser (FEL) for the ablation of soft tissue were first reported in 1994 …

Mid infrared optical parametric oscillator (OPO) as a viable alternative to tissue ablation with the free electron laser (FEL)

MA Mackanos, D Simanovskii, KM Joos… - Lasers in Surgery …, 2007 - Wiley Online Library
Abstract Background and Objectives Investigations with a Mark‐III free electron laser, tuned
to 6.45 µm in wavelength have demonstrated minimal collateral damage and high ablation …

Raman-shifted alexandrite laser for soft tissue ablation in the 6-to 7-µm wavelength range

J Kozub, B Ivanov, A Jayasinghe, R Prasad… - Biomedical optics …, 2011 - opg.optica.org
Prior work with free-electron lasers (FELs) showed that wavelengths in the 6-to 7-µm range
could ablate soft tissues efficiently with little collateral damage; however, FELs proved too …

[PDF][PDF] Импульсно-периодические лазеры на парах стронция и кальция

АН Солдатов, ЕЛ Латуш, ГД Чеботарев - 2012 - vital.lib.tsu.ru
Генерация когерентного излучения к настоящему времени реали зована на самых
разнообразных активных средах и на многих тысячах лазерных переходов [1-10] с …

The effect of free-electron laser pulse structure on mid-infrared soft-tissue ablation: biological effects

MA Mackanos, JA Kozub, DL Hachey… - Physics in Medicine …, 2005 - iopscience.iop.org
Previous studies have shown that changing the pulse structure of the free electron laser
(FEL) from 1 to 200 ps and thus reducing the peak irradiance of the micropulse by 200 times …

6450 nm wavelength tissue ablation using a nanosecond laser based on difference frequency mixing and stimulated Raman scattering

GS Edwards, RD Pearlstein, ML Copeland… - Optics letters, 2007 - opg.optica.org
A four-stage laser system was developed, emitting at a wavelength of 6450 nm with a 3-5 ns
pulse duration,≤ 2 mJ pulse energy, and 1/2 Hz pulse repetition rate. The laser system …

Эффект лазерной резонансной абляции в микрои нанотехнологиях

АН Солдатов, АВ Васильева - Известия Томского …, 2008 - cyberleninka.ru
Обсуждается использование лазеров в микрои нанотехнологиях для аблирования
материалов. Особо выделен класс лазеров с высокими частотами следования …

Comparing an optical parametric oscillator (OPO) as a viable alternative for mid-infrared tissue ablation with a free electron laser (FEL)

MA Mackanos, DM Simanovskii, CH Contag… - Lasers in medical …, 2012 - Springer
Beneficial medical laser ablation removes material efficiently with minimal collateral
damage. A Mark-III free electron laser (FEL), at a wavelength of 6.45 μm has demonstrated …

Исследовательская лазерная установка для резонансной абляции материалов

АН Солдатов, АВ Васильева, АП Ермолаев… - Оптика атмосферы и …, 2006 - elibrary.ru
Спроектирована и создана установка для исследования эффекта резонансной
лазерной абляции таких материалов, как полимеры и биологические ткани. Основу …

[PDF][PDF] Advances in the physical understanding of laser surgery at 6.45 microns

MS Hutson, GS Edwards - … International Free Electron Laser Conference and …, 2004 - cern.ch
We previously presented a model that attributes the wavelength-dependence of FEL tissue
ablation to partitioning of absorbed energy between protein and saline. This energy …