Although nerve cell death is the hallmark of many neurological diseases, the processes
underlying this death are still poorly defined. However, there is a general consensus that …

A comprehensive literature search was performed to collate evidence of mitochondrial
dysfunction in autism spectrum disorders (ASDs) with two primary objectives. First, features …

Minocycline is neuroprotective in animal models of a number of acute CNS injuries and
neurodegenerative diseases. While anti‐inflammatory and anti‐apoptotic effects of …

Vitamin E is a generic term for tocopherols and tocotrienols. This work is based on our
striking evidence that, in neuronal cells, nanomolar concentrations of α-tocotrienol, but not α …

Post-mitotic neurons and heart muscle cells undergo apoptotic cell death in a variety of
acute and chronic degenerative diseases. The intrinsic pathway of apoptosis involves the …

Background and Purpose—The current work is based on our previous finding that in
neuronal cells, nmol/L concentrations of α-tocotrienol (TCT), but not α-tocopherol (TCP) …

Glutathione (GSH), an abundant tripeptidyl molecule, plays pivotal roles in protecting cells
against oxidative stress-induced cellular damage and in detoxifying xenobiotics and drug …

We have identified a group of nutrients that can directly or indirectly protect mitochondria
from oxidative damage and improve mitochondrial function and named them “mitochondrial …

Mitochondria decay with age due to the oxidation of lipids, proteins, RNA, and DNA. Some of
this decay can be reversed in aged animals by feeding them the mitochondrial metabolites …

This review addresses recent and not so recent works that emphasize on the mechanisms
by which liver damage can induce encephalopathy. Hepatic encephalopathy constitutes an …