Serial femtosecond crystallography: the first five years
I Schlichting - IUCrJ, 2015 - journals.iucr.org
Protein crystallography using synchrotron radiation sources has had a tremendous impact
on biology, having yielded the structures of thousands of proteins and given detailed insight …
on biology, having yielded the structures of thousands of proteins and given detailed insight …
Assessing and maximizing data quality in macromolecular crystallography
PA Karplus, K Diederichs - Current opinion in structural biology, 2015 - Elsevier
Highlights•Common data quality indicators grouped as primary, secondary, or
wrong/misleading.•A gedanken experiment reveals shortcomings of some common …
wrong/misleading.•A gedanken experiment reveals shortcomings of some common …
[PDF][PDF] How good are my data and what is the resolution?
PR Evans, GN Murshudov - Acta Crystallographica Section D …, 2013 - journals.iucr.org
Following integration of the observed diffraction spots, the process ofdata reduction'initially
aims to determine the point-group symmetry of the data and the likely space group. This can …
aims to determine the point-group symmetry of the data and the likely space group. This can …
Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system
Flaviviruses, the human pathogens responsible for dengue fever, West Nile fever, tick-borne
encephalitis, and yellow fever, are endemic in tropical and temperate parts of the world. The …
encephalitis, and yellow fever, are endemic in tropical and temperate parts of the world. The …
Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP
Abstract The 70-kilodalton (kDa) heat-shock proteins (Hsp70s) are ubiquitous molecular
chaperones essential for cellular protein folding and proteostasis. Each Hsp70 has two …
chaperones essential for cellular protein folding and proteostasis. Each Hsp70 has two …
Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams
Recent advances in synchrotron sources, beamline optics and detectors are driving a
renaissance in room-temperature data collection. The underlying impetus is the recognition …
renaissance in room-temperature data collection. The underlying impetus is the recognition …
Protein crystallography for aspiring crystallographers or how to avoid pitfalls and traps in macromolecular structure determination
A Wlodawer, W Minor, Z Dauter… - The FEBS journal, 2013 - Wiley Online Library
The number of macromolecular structures deposited in the Protein Data Bank now
approaches 100 000, with the vast majority of them determined by crystallographic methods …
approaches 100 000, with the vast majority of them determined by crystallographic methods …
Fast native-SAD phasing for routine macromolecular structure determination
We describe a data collection method that uses a single crystal to solve X-ray structures by
native SAD (single-wavelength anomalous diffraction). We solved the structures of 11 real …
native SAD (single-wavelength anomalous diffraction). We solved the structures of 11 real …
A brief history of macromolecular crystallography, illustrated by a family tree and its N obel fruits
M Jaskolski, Z Dauter, A Wlodawer - The FEBS journal, 2014 - Wiley Online Library
As a contribution to the celebration of the year 2014, declared by the United Nations to be
'The International Year of Crystallography', the FEBS Journal is dedicating this issue to …
'The International Year of Crystallography', the FEBS Journal is dedicating this issue to …
Metal‐Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction
DNA double helices containing metal‐mediated DNA (mmDNA) base pairs are constructed
from Ag+ and Hg2+ ions between pyrimidine: pyrimidine pairs with the promise of …
from Ag+ and Hg2+ ions between pyrimidine: pyrimidine pairs with the promise of …