Protective effect of ginsenoside Rh2 against Toxoplasma gondii infection-induced neuronal injury through binding TgCDPK1 and NLRP3 to inhibit microglial NLRP3 …
GN Jin, JM Lu, HW Lan, YN Lu, XY Shen, X Xu… - International …, 2022 - Elsevier
Background Toxoplasma gondii (T. gondii) is a neurotropic obligate intracellular parasite
that can activate microglial and promote neuronal apoptosis, leading to central nervous …
that can activate microglial and promote neuronal apoptosis, leading to central nervous …
Toxoplasma gondii inhibits the expression of autophagy-related genes through AKT-dependent inactivation of the transcription factor FOXO3a
AF Diez, LP Leroux, S Chagneau, A Plouffe, M Gold… - Mbio, 2023 - Am Soc Microbiol
The intracellular parasite Toxoplasma gondii induces host AKT activation to prevent
autophagy-mediated clearance; however, the molecular underpinnings are not fully …
autophagy-mediated clearance; however, the molecular underpinnings are not fully …