Apoptotic bodies: bioactive treasure left behind by the dying cells with robust diagnostic and therapeutic application potentials

L Yu, G Zhu, Z Zhang, Y Yu, L Zeng, Z Xu… - Journal of …, 2023 - Springer
Apoptosis, a form of programmed cell death, is essential for growth and tissue homeostasis.
Apoptotic bodies (ApoBDs) are a form of extracellular vesicles (EVs) released by dying cells …

Acute graft-versus-host disease of the gut: considerations for the gastroenterologist

S Naymagon, L Naymagon, SY Wong, HM Ko… - Nature Reviews …, 2017 - nature.com
Haematopoietic stem cell transplantation (HSCT) is central to the management of many
haematological disorders. A frequent complication of HSCT is acute graft-versus-host …

[HTML][HTML] NIH Consensus development project on criteria for clinical trials in chronic graft-versus-host disease: II. The 2014 Pathology Working Group Report

HM Shulman, DM Cardona, JK Greenson… - Biology of Blood and …, 2015 - Elsevier
Abstract The 2005 National Institute of Health (NIH) Consensus Conference outlined
histopathological diagnostic criteria for the major organ systems affected by both acute and …

Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease

SJ Divito, AT Aasebø, TR Matos… - The Journal of …, 2020 - Am Soc Clin Investig
Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality in
hematopoietic stem cell transplantation (HSCT). Donor T cells are key mediators in …

Advances in biological functions and applications of apoptotic vesicles

X Zou, Q Lei, X Luo, J Yin, S Chen, C Hao… - Cell Communication and …, 2023 - Springer
Background Apoptotic vesicles are extracellular vesicles generated by apoptotic cells that
were previously regarded as containing waste or harmful substances but are now thought to …

Extracellular nucleic acids in urine: sources, structure, diagnostic potential

OE Bryzgunova, PP Laktionov - Acta Naturae (англоязычная …, 2015 - cyberleninka.ru
Cell-free nucleic acids (cfNA) may reach the urine through cell necrosis or apoptosis, active
secretion of nucleic acids by healthy and tumor cells of the urinary tract, and transport of …

Hematopoietic stem cell transplantation: graft versus host disease and pathology of gastrointestinal tract, liver, and lung

N Kambham, JP Higgins, U Sundram… - Advances in anatomic …, 2014 - journals.lww.com
Hematopoietic stem cell transplantation (HCT), formerly known as bone marrow
transplantation, is an integral part of treatment for many hematological malignancies. HCT is …

Apoptotic colopathy: a pragmatic approach to diagnosis

DM Karamchandani, R Chetty - Journal of clinical pathology, 2018 - jcp.bmj.com
'Apoptotic colopathy'is an umbrella term signifying a pattern of injury where the
gastrointestinal biopsy shows a colitic picture with apoptosis as the predominant histological …

Tailoring of apoptotic bodies for diagnostic and therapeutic applications: advances, challenges, and prospects

X Miao, X Wu, W You, K He, C Chen, JL Pathak… - Journal of Translational …, 2024 - Springer
Apoptotic bodies (ABs) are extracellular vesicles released during apoptosis and possess
diverse biological activities. Initially, ABs were regarded as garbage bags with the main …

Gastrointestinal pathology in transplant patients

NACS Wong - Histopathology, 2015 - Wiley Online Library
The assessment of gastrointestinal (GI) specimens from transplant patients is complicated by
the wide range of potentially rare pathologies that may be found in this clinical setting. Acute …