The three main mosquito genera, Anopheles, Aedes and Culex, transmit respectively
malaria, dengue and lymphatic filariasis. Current mosquito control strategies have proved …

Aedes mosquitoes include important vector species such as Aedes aegypti, the major vector
of dengue. Genetic control methods are being developed for several of these species …

Mosquito-borne pathogens place an enormous burden on human health. The existing toolkit
is insufficient to support ongoing vector-control efforts towards meeting disease elimination …

Insect-borne diseases cause significant human morbidity and mortality. Current control and
preventive methods against vector-borne diseases rely mainly on insecticides. The …

Malaria is one of the deadliest diseases. Because of the ineffectiveness of current malaria-
control methods, several novel mosquito vector-based control strategies have been …

The piggyBac transposon superfamily is a relatively recently recognized transposon
superfamily. The original piggyBac transposon was isolated from the genome of the …

Background Medical entomologists increasingly recognize that the ability to make
inferences between laboratory experiments of vector biology and epidemiological trends …

The sterile insect technique (SIT) relies on area-wide mass-releases of sterile male pest
insects, which mate with their wild counterparts and thereby cause a drop in the wild …

Transposon-mediated transgenesis of mosquito vectors of disease pathogens followed the
early success of transgenesis in the vinegar fly, Drosophila melanogaster. The P …

Creating transgenic insects is a key technology in insect genetics and molecular biology. A
widely used instrument in insect transgenesis is the piggyBac transposase, resulting in …