Antibiotic combination therapy against resistant bacterial infections: synergy, rejuvenation and resistance reduction

ARM Coates, Y Hu, J Holt, P Yeh - Expert review of Anti-infective …, 2020 - Taylor & Francis
ABSTRACT Introduction: Anti-Microbial Resistance (AMR) is a pandemic which threatens
modern medicine. There is a lack of effective drug treatment due to the slow pace, high cost …

Inorganic polyphosphate: essential for growth and survival

NN Rao, MR Gómez-García… - Annual review of …, 2009 - annualreviews.org
Inorganic polyphosphate (Poly P) is a polymer of tens to hundreds of phosphate residues
linked by “high-energy” phosphoanhydride bonds as in ATP. Found in abundance in all cells …

[HTML][HTML] Metallo-beta-lactamases among imipenem-resistant Pseudomonas aeruginosa in a Brazilian university hospital

MRG Franco, HH Caiaffa-Filho, MN Burattini, F Rossi - Clinics, 2010 - Elsevier
INTRODUCTION: Imipenem-resistant Pseudomonas aeruginosa resulting from metallo-β-
lactamases has been reported to be an important cause of nosocomial infection and is a …

Natural outer membrane permeabilizers boost antibiotic action against irradiated resistant bacteria

HA Farrag, N Abdallah, MMK Shehata… - Journal of Biomedical …, 2019 - Springer
Background This study sought to develop new strategies for reverting the resistance of
pathogenic Gram-negative bacilli by a combination of conventional antibiotics, potent …

Investigation of metallo beta lactamases and oxacilinases in carbapenem resistant Acinetobacter baumannii strains isolated from inpatients

MD Aksoy, Ş Çavuşlu, HM Tuğrul - Balkan medical journal, 2015 - dergipark.org.tr
Background: Resistance to beta-lactam antibiotics is widespread among Acinetobacter
strains. Plasmid-mediated metallo beta lactamases (MBL) are responsible for carbapenem …

Detection of metallo-beta lactamases and oxacillinase genes in carbapenem-resistant Acinetobacter baumannii strains isolated in Morocco

A Massik, L Hibaoui, B Arhoune, G Yahyaoui… - Pan African Medical …, 2021 - ajol.info
Introduction: resistance to carbapenem is widespread among Acinetobacter baumannii (A.
baumannii) strains. Metallo-beta lactamases enzymes (MBL) are responsible for …

Molecular Detection of Medically Important Carbapenemases Genes Expressed by Metallo-β-lactamase Producer Isolates of Pseudomonas aeruginosa and …

MTS Al-Ouqaili - Asian Journal of Pharmaceutics (AJP), 2018 - asiapharmaceutics.info
Abstract Background and Objectives: The increase in antibiotic resistance among
Pseudomonas aeruginosa and Klebsiella pneumoniae especially through the production of …

Investigation of metallo-beta-lactamase producing strains of Pseudomonas aeruginosa and Acinetobacter baumannii by E-test, disk synergy and PCR

Z Aktaş, ÇB Kayacan - Scandinavian journal of infectious diseases, 2008 - Taylor & Francis
Carbapenem non-susceptible Pseudomonas aeruginosa and Acinetobacter baumannii
strains were tested for the presence of metallo-beta-lactamases (MBLs) by EDTA-synergy …

Emergence of bla VEB and bla GES among VIM-producing Pseudomonas aeruginosa clinical isolates in …

A Gaballah, A Elbaradei, A Elsheredy… - Acta Microbiologica et …, 2019 - akjournals.com
Thirty-three Pseudomonas aeruginosa isolates, resistant to one or more β-lactams, were
included in this study. Identification of tested strains was confirmed using MALDI-TOF/MS …

Phenotypic and molecular characterization of extended spectrum- and metallo- beta lactamase producing Pseudomonas aeruginosa clinical isolates from Egypt

EA Edward, MR El Shehawy, A Abouelfetouh… - Infection, 2024 - Springer
Abstract Background Antimicrobial resistance among Pseudomonas aeruginosa (P.
aeruginosa), a leading cause of nosocomial infections worldwide, is escalating. This study …