Cancer progression with uncontrolled tumor growth, local invasion, and metastasis depends
largely on the proteolytic activity of numerous matrix metalloproteinases (MMPs), which …

Simple Summary MMP9, due to its proteolytic activity, plays a key role in tumorigenesis by
regulating migration, epithelial-to-mesenchymal transition and survival of cancer cells …

Pulmonary arterial hypertension (PAH) is characterized by remodeling of the extracellular
matrix (ECM) of the pulmonary arteries with increased collagen deposition, cross-linkage of …

Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and
idiopathic pulmonary fibrosis (IPF), are characterized by regional extracellular matrix (ECM) …

Pulmonary hypertension is a progressive and often fatal cardiopulmonary condition
characterised by increased pulmonary arterial pressure, structural changes in the pulmonary …

Pulmonary hypertension worsens outcome in left heart disease. Stiffening of the pulmonary
artery may drive this pathology by increasing right ventricular dysfunction and lung vascular …

(-)-Epigallocatechin-3-gallate (EGCG) is a major polyphenol of green tea that possesses a
wide variety of actions. EGCG acts as a strong antioxidant which effectively scavenges …

Pulmonary arterial hypertension (PAH) is a severe vasculopathy characterized by the
presence of fibrotic lesions in the arterial wall and the loss of small distal pulmonary arteries …

Endothelial cells (ECs) are a key cellular component of the vascular system as they form the
inner lining of the blood vessels. Recent findings highlight that ECs express extensive …

Dedication This review is dedicated in the memory of Dr Radha K. Maheshwari, a great
mentor and colleague, whose passion for research and student training has left a lasting …