miR-155 in cancer drug resistance and as target for miRNA-based therapeutics

R Bayraktar, K Van Roosbroeck - Cancer and Metastasis Reviews, 2018 - Springer
Small non-coding microRNAs (miRNAs) are instrumental in physiological processes, such
as proliferation, cell cycle, apoptosis, and differentiation, processes which are often …

MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics

A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …

Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice

ED Koval, C Shaner, P Zhang… - Human molecular …, 2013 - academic.oup.com
Abstract microRNAs (miRNAs) are dysregulated in a variety of disease states, suggesting
that this newly discovered class of gene expression repressors may be viable therapeutic …

MicroRNA targeting by quercetin in cancer treatment and chemoprotection

DH Kim, H Khan, H Ullah, STS Hassan… - Pharmacological …, 2019 - Elsevier
A growing number of evidences from clinical and preclinical studies have shown that
dysregulation of microRNA (miRNA) function contributes to the progression of cancer and …

Crosstalk between miRNAs and DNA Methylation in Cancer

M Saviana, P Le, L Micalo, D Del Valle-Morales… - Genes, 2023 - mdpi.com
miRNAs are some of the most well-characterized regulators of gene expression. Integral to
several physiological processes, their aberrant expression often drives the pathogenesis of …

MicroRNAs in glioblastoma pathogenesis and therapy: A comprehensive review

BK Ahir, H Ozer, HH Engelhard, SS Lakka - Critical Reviews in Oncology …, 2017 - Elsevier
Glioblastoma (GBM), also known as grade IV astrocytoma, is the most aggressive primary
intracranial tumor of the adult brain. MicroRNAs (miRNAs), a class of small non-coding RNA …

The process and regulatory components of inflammation in brain oncogenesis

AGM Mostofa, SR Punganuru, HR Madala… - Biomolecules, 2017 - mdpi.com
Central nervous system tumors comprising the primary cancers and brain metastases
remain the most lethal neoplasms and challenging to treat. Substantial evidence points to a …

Roles of the miR-155 in neuroinflammation and neurological disorders: a potent biological and therapeutic target

SH Rastegar-Moghaddam… - Cellular and molecular …, 2023 - Springer
Neuroinflammation plays a crucial role in the development and progression of neurological
disorders. MicroRNA-155 (miR-155), a miR is known to play in inflammatory responses, is …

[HTML][HTML] microRNA-155 regulates cell proliferation and invasion by targeting FOXO3a in glioma

N Ling, J Gu, Z Lei, M Li, J Zhao… - Oncology …, 2013 - spandidos-publications.com
Abstract microRNAs (miRNAs) are short noncoding RNAs, which modulate the expression of
numerous genes by targeting mRNAs. Numerous abnormal miRNA expression patterns are …

Integrating Multi-Omics analysis for enhanced diagnosis and treatment of glioblastoma: A comprehensive Data-Driven approach

A Barzegar Behrooz, H Latifi-Navid, SC da Silva Rosa… - Cancers, 2023 - mdpi.com
Simple Summary The most prevalent and lethal primary brain tumor, glioblastoma
multiforme (GBM), exhibits fast growth and widespread invasion and has a poor prognosis …