Genetic polymorphism in angiotensinogen and its association with cardiometabolic diseases

M Shahid, K Rehman, MSH Akash, S Suhail, S Kamal… - Metabolites, 2022 - mdpi.com
Angiotensinogen (AGT) is one of the most significant enzymes of the renin-angiotensin-
aldosterone system (RAAS) which is involved in the regulation and maintenance of blood …

Computational and pharmacogenomic insights on hypertension treatment: rational drug design and optimization strategies

L Loganathan, K Gopinath… - Current Drug …, 2020 - ingentaconnect.com
Background: Hypertension is a prevalent cardiovascular complication caused by genetic
and nongenetic factors. Blood pressure (BP) management is difficult because most patients …

Association of ACE gene A2350G and I/D polymorphisms with essential hypertension in the northernmost province of China

F Sun, N He, K Zhang, N Wu, J Zhao… - Clinical and experimental …, 2018 - Taylor & Francis
Angiotensin converting enzyme (ACE) gene, as a strong candidate gene for essential
hypertension (EH), has been extensively studied. In this study, we carried out a population …

[HTML][HTML] Angiotensinogen (AGT) M235T, AGT T174M and angiotensin-1-converting enzyme (ACE) I/D gene polymorphisms in essential hypertension: effects on …

V Kolovou, E Lagou, C Mihas, G Vasiliki… - The open …, 2015 - ncbi.nlm.nih.gov
Background: Hypertension, one of the most important risk factors for premature
cardiovascular disease, is a major worldwide public health problem. Angiotensin-1 …

Correlation between renin-angiotensin system gene polymorphisms and essential hypertension in the Chinese Yi ethnic group

YL Yang, YP Mo, YS He, F Yang, Y Xu… - Journal of the Renin …, 2015 - journals.sagepub.com
Introduction: The renin-angiotensin system (RAS) has been considered to play an important
role in the regulation of blood pressure. This study aimed to investigate the correlation …

Renin-angiotensin system gene polymorphisms and high blood pressure in Lithuanian children and adolescents

S Simonyte, R Kuciene, J Medzioniene… - BMC Medical …, 2017 - Springer
Background Epidemiological studies have demonstrated the influence of environmental
factors on HBP in the population of Lithuanian children, although the role of genetic factors …

Polymorphisms in the Renin-Angiotensin System and eNOS Glu298Asp Genes Are Associated with Increased Risk for Essential Hypertension in a Mexican …

I Isordia-Salas, D Santiago-Germán… - Journal of the Renin …, 2023 - journals.sagepub.com
Background. Essential hypertension is the result of modifiable and genetic factors, and it is
associated with increased risk for atherothrombosis. Some polymorphisms are associated …

Association and Interaction Effect of AGTR1 and AGTR2 Gene Polymorphisms with Dietary Pattern on Metabolic Risk Factors of Cardiovascular Disease in …

RWK Yap, Y Shidoji, WS Yap, M Masaki - Nutrients, 2017 - mdpi.com
Gene-diet interaction using a multifactorial approach is preferred to study the multiple risk
factors of cardiovascular disease (CVD). This study examined the association and gene-diet …

RAS genetic variants in interaction with ACE inhibitors drugs influences essential hypertension control

F Heidari, R Vasudevan, SZM Ali, P Ismail… - Archives of medical …, 2017 - Elsevier
Backgrounds and Aims Essential Hypertension (EH) is a common disorder associated with
increased cardiovascular morbidity and mortality in Malaysia. To investigate how genetic …

Factors affecting the urinary aldosterone-to-creatinine ratio in healthy dogs and dogs with naturally occurring myxomatous mitral valve disease

A Galizzi, M Bagardi, A Stranieri, AM Zanaboni… - BMC veterinary …, 2021 - Springer
Background Chronic renin-angiotensin-aldosterone system (RAAS) activation in course of
heart diseases contributes to cardiac remodeling and heart failure. Myxomatous mitral valve …