In the CNS, iron in several proteins is involved in many important processes such as oxygen
transportation, oxidative phosphorylation, myelin production, and the synthesis and …

In MRI, the main magnetic field polarizes the electron cloud of a molecule, generating a
chemical shift for observer protons within the molecule and a magnetic susceptibility …

Magnetic susceptibility describes the magnetizability of a material to an applied magnetic
field and represents an important parameter in the field of MRI. With the recently introduced …

BACKGROUND. In some active multiple sclerosis (MS) lesions, a strong immune reaction at
the lesion edge may contain growth and thereby isolate the lesion from the surrounding …

Quantitative susceptibility mapping (QSM) is a recently developed MRI technique that
provides a quantitative measure of tissue magnetic susceptibility. To compute tissue …

This review discusses the major contributors to the subtle magnetic properties of brain tissue
and how they affect MRI contrast. With the increased availability of high‐field scanners, the …

Purpose To assess multiple sclerosis (MS) lesions at various ages by using quantitative
susceptibility mapping (QSM) and conventional magnetic resonance (MR) imaging …

Over the past few decades, MRI-based visualization of demyelinated CNS lesions has
become pivotal to the diagnosis and monitoring of multiple sclerosis (MS). In this Review, we …

Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

Objective In multiple sclerosis (MS), accurate, in vivo characterization of dynamic
inflammatory pathological changes occurring in newly forming lesions could have major …