Although involvement of the liver and biliary tract has been recognized as a complication of
cystic fibrosis (CF) since Anderson's initial description of CF in 1938 (1), the clinical …

Cystic fibrosis is the most common, lethal, genetic defect of white populations (1). Once
limited largely to infants and children, the immediate prognosis has changed drastically over …

The median age of the population with cystic fibrosis (CF) has increased worldwide, which
has led to the suggestion that the prevalence of liver disease would increase. The aim of this …

Splenomegaly is a frequent finding in patients with liver disease. It is usually asymptomatic
but may cause hypersplenism. Thrombocytopenia is the most frequent manifestation of …

To assess the prevalence, demography, and clinical features of liver disease among
patients with cystic fibrosis the case notes of 524 patients of all ages who were attending the …

Cystic fibrosis is now the most common cause of chronic obstructive pulmonary disease
(COPD) and of pancreatic insufficiency in the first three decades of life in the United States …

Background/Aim: Variceal bleeding is the most severe complication in patients with cystic
fibrosis-associated liver cirrhosis, who often do not have severe respiratory failure. The …

To study the liver disease of patients with cystic fibrosis, percutaneous liver biopsies were
performed in 10 patients with cystic fibrosis aged 6 to 22 yr. Nine of 10 patients had high …

Objectives Liver disease is the second cause of death in cystic fibrosis. The most deleterious
complication of liver disease is portal hypertension, which has an estimated prevalence of …

Purpose: To explain the rationale supporting the use of ursodiol (ursodeoxycholic acid) for
the treatment of patients with cholesterol gallstones and chronic liver diseases and to …