Protein prenylation: unique fats make their mark on biology

M Wang, PJ Casey - Nature reviews Molecular cell biology, 2016 - nature.com
The modification of eukaryotic proteins by isoprenoid lipids, which is known as prenylation,
controls the localization and activity of a range of proteins that have crucial functions in …

Regulation of Cell Wall Biogenesis in Saccharomyces cerevisiae: The Cell Wall Integrity Signaling Pathway

DE Levin - Genetics, 2011 - academic.oup.com
The yeast cell wall is a strong, but elastic, structure that is essential not only for the
maintenance of cell shape and integrity, but also for progression through the cell cycle …

[图书][B] Biochemistry

D Voet, JG Voet - 2010 - books.google.com
The “Gold Standard” in Biochemistry text books. Biochemistry 4e, is a modern classic that
has been thoroughly revised. Don and Judy Voet explain biochemical concepts while …

Role of lipids in the formation and maintenance of the cutaneous permeability barrier

KR Feingold, PM Elias - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
The major function of the skin is to form a barrier between the internal milieu and the hostile
external environment. A permeability barrier that prevents the loss of water and electrolytes …

Fruits: a developmental perspective.

G Gillaspy, H Ben-David, W Gruissem - The Plant Cell, 1993 - ncbi.nlm.nih.gov
Embryonic development in many angiosperms occurs concomitantly with the development
of the ovary into a specialized organ, the fruit, which provides a suitable environment for …

Protein prenylation: molecular mechanisms and functional consequences

FL Zhang, PJ Casey - Annual review of biochemistry, 1996 - annualreviews.org
Prenylation is a class of lipid modification involving covalent addition of either farnesyl (15-
carbon) or geranylgeranyl (20-carbon) isoprenoids to conserved cysteine residues at or …

Palmitoylation: policing protein stability and traffic

ME Linder, RJ Deschenes - Nature reviews Molecular cell biology, 2007 - nature.com
Palmitate modifies both peripheral and integral membrane proteins and its addition can be
permanent or transient, which makes it unique among the lipid modifications of proteins. The …

[图书][B] Bioassay techniques for drug development

MI Choudhary, WJ Thomsen - 2001 - taylorfrancis.com
The goal of an activity-directed isolation process is to isolate bioactive compounds which
may provide structural leads of therapeutic importance. Whereas the traditional process of …

Cell Wall Integrity Signaling in Saccharomyces cerevisiae

DE Levin - Microbiology and molecular biology reviews, 2005 - Am Soc Microbiol
The yeast cell wall is a highly dynamic structure that is responsible for protecting the cell
from rapid changes in external osmotic potential. The wall is also critical for cell expansion …

Detecting subtle sequence signals: a Gibbs sampling strategy for multiple alignment

CE Lawrence, SF Altschul, MS Boguski, JS Liu… - science, 1993 - science.org
A wealth of protein and DNA sequence data is being generated by genome projects and
other sequencing efforts. A crucial barrier to deciphering these sequences and …