UW supplementation with AP39 improves liver viability following static cold storage

ML Taggart, S Holkup, A Tchir, M Mojoudi, A Lyon… - Scientific Reports, 2025 - nature.com
Static cold storage of donor livers at 4° C incompletely arrests metabolism, ultimately leading
to decreases in ATP levels, oxidative stress, cell death, and organ failure. Hydrogen Sulfide …

A Multidrug Donor Preconditioning Improves Steatotic Rat Liver Allograft Function and Recipient Survival After Transplantation

M Xu, SM Alwahsh, MH Kim… - Transplant …, 2024 - frontierspartnerships.org
The scarcity of donors has prompted the growing utilization of steatotic livers, which are
susceptible to injuries following orthotopic liver transplantation (OLT). This study aims to …

Two‐day Static Cold Preservation of α1, 3‐Galactosyltransferase Knockout Kidney Grafts Before Simulated Xenotransplantation

M Mojoudi, ML Taggart, A Karadagi… - …, 2024 - Wiley Online Library
Transplantation remains the preferred treatment for end‐stage kidney disease but is critically
limited by the number of available organs. Xenografts from genetically modified pigs have …

Ex Vivo Machine Perfusion as a Platform for Lentiviral Gene Delivery in Rat Livers

K Uygun, IF von Reiterdank, M Mojoudi… - Research …, 2024 - pmc.ncbi.nlm.nih.gov
Developing new strategies for local monitoring and delivery of immunosuppression is critical
to making allografts safer and more accessible. Ex vivo genetic modification of grafts using …

UW Supplementation with AP39 Improves Liver Viability Following Static Cold Storage

ST McLean, S Holkup, A Tchir, M Mojoudi, M Hassan… - 2024 - researchsquare.com
Static cold storage of donor livers at 4 C incompletely arrests metabolism, ultimately leading
to decreases in ATP levels, oxidative stress, cell death, and organ failure. Hydrogen Sulfide …