Toxicity of amphetamines: an update

M Carvalho, H Carmo, VM Costa, JP Capela… - Archives of …, 2012 - Springer
Amphetamines represent a class of psychotropic compounds, widely abused for their
stimulant, euphoric, anorectic, and, in some cases, emphathogenic, entactogenic, and …

[图书][B] Karch's pathology of drug abuse

SB Karch, O Drummer - 2008 - taylorfrancis.com
Written for practitioners in the field, this critically acclaimed bestseller provides authoritative
information focused on the investigation of drug-related deaths and practical approaches to …

Mechanisms underlying the hepatotoxic effects of ecstasy

M Carvalho, H Pontes, F Remiao… - Current …, 2010 - ingentaconnect.com
3, 4-Methylenedioxymethamphetamine (MDMA or ecstasy) is a worldwide illegally used
amphetamine-derived designer drug known to be hepatotoxic to humans. Jaundice …

Acute administration of 3, 4-methylenedioxymethamphetamine (MDMA) induces oxidative stress, lipoperoxidation and TNFα-mediated apoptosis in rat liver

D Cerretani, S Bello, S Cantatore, AI Fiaschi… - Pharmacological …, 2011 - Elsevier
Liver toxicity is one of the consequences of ecstasy (3, 4-methylenedioxymethamphetamine
MDMA) abuse and hepatocellular damage is reported after MDMA consumption. Various …

Cardiac oxidative stress determination and myocardial morphology after a single ecstasy (MDMA) administration in a rat model

D Cerretani, I Riezzo, AI Fiaschi, F Centini… - International journal of …, 2008 - Springer
Experimental and clinical data indicate that 3, 4-methylenedioxy-N-methylamphetamine
(MDMA) abuse can produce significant cardiovascular toxicity. A mechanism may be a direct …

Cytotoxic effects of 3,4-methylenedioxy-N-alkylamphetamines, MDMA and its analogues, on isolated rat hepatocytes

Y Nakagawa, T Suzuki, S Tayama, H Ishii, A Ogata - Archives of toxicology, 2009 - Springer
The amphetamine-derived designer drugs have been illegally used worldwide as
recreational drugs, some of which are known to be hepatotoxic in humans. To compare their …

Ecstasy produces left ventricular dysfunction and oxidative stress in rats

SK Shenouda, KC Lord, E McIlwain… - Cardiovascular …, 2008 - academic.oup.com
Aims Our aim was to determine whether the repeated, binge administration of 3, 4-
methylenedioxymethamphetamine (ecstasy; MDMA) produces structural and/or functional …

Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes

SK Shenouda, KJ Varner, F Carvalho… - Cardiovascular …, 2009 - Springer
Abstract Repeated administration of 3, 4-methylenedioxymethamphetamine
(MDMA)(ecstasy) produces eccentric left ventricular (LV) dilation and diastolic dysfunction …

Cytotoxic effects of psychotropic benzofuran derivatives, N‐methyl‐5‐(2‐aminopropyl)benzofuran and its N‐demethylated derivative, on isolated rat hepatocytes

Y Nakagawa, T Suzuki, Y Tada… - Journal of Applied …, 2017 - Wiley Online Library
The novel psychoactive compounds derived from amphetamine have been illegally abused
as recreational drugs, some of which are known to be hepatotoxic in humans and …

Exposure to 3, 4-methylenedioxymethamphetamine (MDMA) induced biochemical but not behavioral effects in Daphnia magna

B De Felice, M Parolini - Environmental Toxicology and Pharmacology, 2023 - Elsevier
Among amphetamine like stimulants (ATS), the 3, 4-methylenedioxymethamphetamine
(MDMA) is often detected in sewage and surface waters, representing a potential threat for …