The pivotal role of the placenta in normal and pathological pregnancies: a focus on preeclampsia, fetal growth restriction, and maternal chronic venous disease

MA Ortega, O Fraile-Martínez, C García-Montero… - Cells, 2022 - mdpi.com
The placenta is a central structure in pregnancy and has pleiotropic functions. This organ
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …

Placental trophoblast cell differentiation: physiological regulation and pathological relevance to preeclampsia

L Ji, J Brkić, M Liu, G Fu, C Peng, YL Wang - Molecular aspects of medicine, 2013 - Elsevier
The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

Biological functions of hCG and hCG-related molecules

LA Cole - Reproductive Biology and Endocrinology, 2010 - Springer
Background hCG is a term referring to 4 independent molecules, each produced by
separate cells and each having completely separate functions. These are hCG produced by …

hCG: biological functions and clinical applications

C Nwabuobi, S Arlier, F Schatz… - International journal of …, 2017 - mdpi.com
Human chorionic gonadotropin (hCG) is produced primarily by differentiated
syncytiotrophoblasts, and represents a key embryonic signal that is essential for the …

Intrauterine trophoblast migration: A comparative view of humans and rodents

JF Silva, R Serakides - Cell adhesion & migration, 2016 - Taylor & Francis
Trophoblast migration and invasion through the decidua and maternal uterine spiral arteries
are crucial events in placentation. During this process, invasive trophoblast replace vascular …

Applications of electrochemical immunosensors for early clinical diagnostics

EB Bahadır, MK Sezgintürk - Talanta, 2015 - Elsevier
Cancer and cardiovascular diseases are the major threats to global health. Hence, there is a
growing demand for a range of portable, rapid and low cost biosensing devices for the …

[HTML][HTML] Critical growth factors and signalling pathways controlling human trophoblast invasion

M Knöfler - The International journal of developmental biology, 2010 - ncbi.nlm.nih.gov
Invasion of placental trophoblasts into uterine tissue and vessels is an essential process of
human pregnancy and fetal development. Due to their remarkable plasticity invasive …

Models for study of human embryo implantation: choice of cell lines?

NJ Hannan, P Paiva, E Dimitriadis… - Biology of …, 2010 - academic.oup.com
Implantation failure and inadequate placental development are important contributors to
infertility, recurrent miscarriage, and other pregnancy-related problems in women. Better …

New discoveries on the biology and detection of human chorionic gonadotropin

LA Cole - Reproductive Biology and Endocrinology, 2009 - Springer
Human chorionic gonadotropin (hCG) is a glycoprotein hormone comprising 2 subunits,
alpha and beta joined non covalently. While similar in structure to luteinizing hormone (LH) …

hCGs: different sources of production, different glycoforms and functions

T Fournier, J Guibourdenche, D Evain-Brion - Placenta, 2015 - Elsevier
Human chorionic gonadotropin (hCG) is the first hormonal message from the placenta to the
mother. It is detectable in maternal blood two days after implantation and behaves like an …