Research into cancer therapeutics has uncovered various potential medications based on metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
M Mavvaji, S Akkoc - ChemistrySelect, 2023 - Wiley Online Library
Cancer, one of the most deadly diseases worldwide, is still a crucial challenge to human well‐being. Hence, the design and development of modern protocols to cure diverse kinds …
Improving lipophilicity for drugs to penetrate the lipid membrane and decreasing bacterial and fungal coinfections for patients with cancer pose challenges in the drug development …
S Kumar, I Ali, F Abbas, A Rana, S Pandey… - Journal of …, 2023 - Taylor & Francis
Lung cancer is a complex and heterogeneous disease, which has been associated with various molecular alterations, including the overexpression and mutations of the epidermal …
Silver has a long history of antimicrobial activity and received an increasing interest in last decades owing to the rise in antimicrobial resistance. The major drawback is the limited …
EM Husseiny, HS Abulkhair, SSA El-Hddad… - Future Medicinal …, 2023 - Taylor & Francis
Aim: A fragment-based design and synthesis of three novel series of aminopyridone-linked benzimidazoles as potential anticancer candidates with significant CDK9 inhibition was …
Erratic cell proliferation is the initial symptom of cancer, which can eventually metastasize to other organs. Before cancer becomes metastatic, its spread is triggered by pro-angiogenic …
Benzimidazole type N‐heterocyclic carbene molecules and their metal complexes have well‐ known biological activity. Elemental silver and silver complexes also have antibacterial and …
Energetic heterocycles, including pyridines, triazoles, and tetrazoles, exhibit greater density, heats of formation, and oxygen balance compared to their carbocyclic counterparts, making …