Breathing matters

CA Del Negro, GD Funk, JL Feldman - Nature Reviews Neuroscience, 2018 - nature.com
Breathing is a well-described, vital and surprisingly complex behaviour, with behavioural
and physiological outputs that are easy to directly measure. Key neural elements for …

Brainstem respiratory networks: building blocks and microcircuits

JC Smith, APL Abdala, A Borgmann, IA Rybak… - Trends in …, 2013 - cell.com
Breathing movements in mammals are driven by rhythmic neural activity generated within
spatially and functionally organized brainstem neural circuits comprising the respiratory …

Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells

DP Hoffman, G Shtengel, CS Xu, KR Campbell… - Science, 2020 - science.org
INTRODUCTION Our textbook understanding of the nanoscale organization of the cell and
its relationship to the thousands of proteins that drive cellular metabolism comes largely from …

Piezo2 is required for Merkel-cell mechanotransduction

SH Woo, S Ranade, AD Weyer, AE Dubin, Y Baba… - Nature, 2014 - nature.com
How we sense touch remains fundamentally unknown,. The Merkel cell–neurite complex is
a gentle touch receptor in the skin that mediates slowly adapting responses of Aβ sensory …

Genetic architecture of subcortical brain structures in 38,851 individuals

CL Satizabal, HHH Adams, DP Hibar, CC White… - Nature …, 2019 - nature.com
Subcortical brain structures are integral to motion, consciousness, emotions and learning.
We identified common genetic variation related to the volumes of the nucleus accumbens …

Hox genes: choreographers in neural development, architects of circuit organization

P Philippidou, JS Dasen - Neuron, 2013 - cell.com
The neural circuits governing vital behaviors, such as respiration and locomotion, are
comprised of discrete neuronal populations residing within the brainstem and spinal cord …

[HTML][HTML] bHLH transcription factors in neural development, disease, and reprogramming

DJ Dennis, S Han, C Schuurmans - Brain research, 2019 - Elsevier
The formation of functional neural circuits in the vertebrate central nervous system (CNS)
requires that appropriate numbers of the correct types of neuronal and glial cells are …

Skilled reaching relies on a V2a propriospinal internal copy circuit

E Azim, J Jiang, B Alstermark, TM Jessell - Nature, 2014 - nature.com
The precision of skilled forelimb movement has long been presumed to rely on rapid
feedback corrections triggered by internally directed copies of outgoing motor commands …

Understanding the rhythm of breathing: so near, yet so far

JL Feldman, CA Del Negro… - Annual review of …, 2013 - annualreviews.org
Breathing is an essential behavior that presents a unique opportunity to understand how the
nervous system functions normally, how it balances inherent robustness with a highly …

[HTML][HTML] Astrocytic trans-differentiation completes a multicellular paracrine feedback loop required for medulloblastoma tumor growth

M Yao, PB Ventura, Y Jiang, FJ Rodriguez, L Wang… - Cell, 2020 - cell.com
The tumor microenvironment (TME) is critical for tumor progression. However, the
establishment and function of the TME remain obscure because of its complex cellular …