Ten steps to becoming a musculoskeletal simulation expert: a half-century of progress and outlook for the future

SD Uhlrich, TK Uchida, MR Lee, SL Delp - Journal of biomechanics, 2023 - Elsevier
Over the past half-century, musculoskeletal simulations have deepened our knowledge of
human and animal movement. This article outlines ten steps to becoming a musculoskeletal …

How mechanics of individual muscle-tendon units define knee and ankle joint function in health and cerebral palsy—a narrative review

CS Kaya Keles, F Ates - Frontiers in bioengineering and …, 2023 - frontiersin.org
This study reviews the relationship between muscle-tendon biomechanics and joint function,
with a particular focus on how cerebral palsy (CP) affects this relationship. In healthy …

Multi-level personalization of neuromusculoskeletal models to estimate physiologically plausible knee joint contact forces in children

G Davico, DG Lloyd, CP Carty, BA Killen… - … and modeling in …, 2022 - Springer
Neuromusculoskeletal models are a powerful tool to investigate the internal biomechanics of
an individual. However, commonly used neuromusculoskeletal models are generated via …

Physics-based simulations to predict the differential effects of motor control and musculoskeletal deficits on gait dysfunction in cerebral palsy: a retrospective case …

A Falisse, L Pitto, H Kainz, H Hoang… - Frontiers in human …, 2020 - frontiersin.org
Physics-based simulations of walking have the theoretical potential to support clinical
decision-making by predicting the functional outcome of treatments in terms of walking …

A conceptual blueprint for making neuromusculoskeletal models clinically useful

BJ Fregly - Applied Sciences, 2021 - mdpi.com
The ultimate goal of most neuromusculoskeletal modeling research is to improve the
treatment of movement impairments. However, even though neuromusculoskeletal models …

[HTML][HTML] Automatic generation of personalised skeletal models of the lower limb from three-dimensional bone geometries

L Modenese, JB Renault - Journal of Biomechanics, 2021 - Elsevier
The generation of personalised and patient-specific musculoskeletal models is currently a
cumbersome and time-consuming task that normally requires several processing hours and …

In silico-enhanced treatment and rehabilitation planning for patients with musculoskeletal disorders: can musculoskeletal modelling and dynamic simulations really …

BA Killen, A Falisse, F De Groote, I Jonkers - Applied Sciences, 2020 - mdpi.com
Over the past decades, the use of computational physics-based models representative of the
musculoskeletal (MSK) system has become increasingly popular in many fields of clinically …

The history and future of neuromusculoskeletal biomechanics

DG Lloyd, I Jonkers, SL Delp… - Journal of Applied …, 2023 - journals.humankinetics.com
The Executive Council of the International Society of Biomechanics has initiated and
overseen the commemorations of the Society's 50th Anniversary in 2023. This included …

Evaluation of synergy extrapolation for predicting unmeasured muscle excitations from measured muscle synergies

D Ao, MS Shourijeh, C Patten, BJ Fregly - Frontiers in computational …, 2020 - frontiersin.org
Electromyography (EMG)-driven musculoskeletal modeling relies on high-quality
measurements of muscle electrical activity to estimate muscle forces. However, a critical …

Discovering individual-specific gait signatures from data-driven models of neuromechanical dynamics

TS Winner, MC Rosenberg, K Jain… - PLOS Computational …, 2023 - journals.plos.org
Locomotion results from the interactions of highly nonlinear neural and biomechanical
dynamics. Accordingly, understanding gait dynamics across behavioral conditions and …