Livestock 2.0–genome editing for fitter, healthier, and more productive farmed animals

C Tait-Burkard, A Doeschl-Wilson, MJ McGrew… - Genome biology, 2018 - Springer
The human population is growing, and as a result we need to produce more food whilst
reducing the impact of farming on the environment. Selective breeding and genomic …

Multi-omic data integration and analysis using systems genomics approaches: methods and applications in animal production, health and welfare

P Suravajhala, LJA Kogelman… - Genetics Selection …, 2016 - Springer
In the past years, there has been a remarkable development of high-throughput omics (HTO)
technologies such as genomics, epigenomics, transcriptomics, proteomics and …

Diversity across major and candidate genes in European local pig breeds

M Muñoz, R Bozzi, F García, Y Núñez, C Geraci… - PloS one, 2018 - journals.plos.org
The aim of this work was to analyse the distribution of causal and candidate mutations
associated to relevant productive traits in twenty local European pig breeds. Also, the …

Functional Annotation of the Transcriptome of the Pig, Sus scrofa, Based Upon Network Analysis of an RNAseq Transcriptional Atlas

KM Summers, SJ Bush, C Wu, AI Su, C Muriuki… - Frontiers in …, 2020 - frontiersin.org
The domestic pig (Sus scrofa) is both an economically important livestock species and a
model for biomedical research. Two highly contiguous pig reference genomes have recently …

Recent genetic advances on boar taint reduction as an alternative to castration: a review

DAS Duarte, M Schroyen, RR Mota… - Journal of Applied …, 2021 - Springer
Boar taint is an unpleasant odor in male pig meat, mainly caused by androstenone, skatole,
and indole, which are deposited in the fat tissue. Piglet castration is the most common …

[HTML][HTML] Genomic selection for boar taint compounds and carcass traits in a commercial pig population

CF de Campos, MS Lopes, FF e Silva, R Veroneze… - Livestock Science, 2015 - Elsevier
This study aimed to compare two different Genome-Wide Selection (GWS) methods (Ridge
Regression BLUP− RR-BLUP and Bayesian LASSO− BL) to predict the genomic estimated …

Genomic prediction and genome-wide association study for boar taint compounds

S Faggion, E Boschi, R Veroneze, P Carnier, V Bonfatti - Animals, 2023 - mdpi.com
Simple Summary Some of the compounds involved in sexual steroids' metabolic pathways
(ie, androstenone, indole, and skatole) might accumulate in the adipose tissue of intact male …

Applying an association weight matrix in weighted genomic prediction of boar taint compounds

ME Botelho, MS Lopes, PK Mathur… - Journal of Animal …, 2021 - Wiley Online Library
Biological information regarding markers and gene association may be used to attribute
different weights for single nucleotide polymorphism (SNP) in genome‐wide selection …

Systems genomics study reveals expression quantitative trait loci, regulator genes and pathways associated with boar taint in pigs

M Drag, MB Hansen, HN Kadarmideen - PloS one, 2018 - journals.plos.org
Boar taint is an offensive odour and/or taste from a proportion of non-castrated male pigs
caused by skatole and androstenone accumulation during sexual maturity. Castration is …

Mulberry leaf supplementation inhibits skatole deposition by regulating gut microbiota and upregulating liver cytochrome P450 1A1 expression in finishing pigs

Y Sun, X Men, T Lin, B Deng, S Zhong, J Huo, K Qin… - Animal Nutrition, 2024 - Elsevier
Skatole, a strong fecal odor substance, is generated through microbial degradation of
tryptophan in the animal hindgut. It easily accumulates in adipose tissue and affects meat …