Thyroid cancer in the pediatric population

VA Paulson, ER Rudzinski, DS Hawkins - Genes, 2019 - mdpi.com
Thyroid cancer is rare in the pediatric population, but thyroid carcinomas occurring in
children carry a unique set of clinical, pathologic, and molecular characteristics. In …

Genetic landscape of papillary thyroid carcinoma and nuclear architecture: an overview comparing pediatric and adult populations

A Rangel-Pozzo, L Sisdelli, MIV Cordioli, F Vaisman… - Cancers, 2020 - mdpi.com
Simple Summary Papillary thyroid carcinoma (PTC) represents 80–90% of all differentiated
thyroid carcinomas. PTC has a high rate of gene fusions and mutations, which can influence …

NTRK fusion oncogenes in pediatric papillary thyroid carcinoma in northeast United States

ML Prasad, M Vyas, MJ Horne, RK Virk, R Morotti… - Cancer, 2016 - Wiley Online Library
BACKGROUND An increase in thyroid cancers, predominantly papillary thyroid carcinoma
(PTC), has been recently reported in children. METHODS The histopathology of 28 …

Fusion oncogenes are the main genetic events found in sporadic papillary thyroid carcinomas from children

MICV Cordioli, L Moraes, AU Bastos, P Besson… - Thyroid, 2017 - liebertpub.com
Background: Previous studies reported significant differences in the clinical presentation
and outcomes of papillary thyroid carcinoma (PTC) in pediatric patients compared with …

BRAFV600E mutation is highly prevalent in thyroid carcinomas in the young population in Fukushima: a different oncogenic profile from Chernobyl

N Mitsutake, T Fukushima, M Matsuse… - Scientific reports, 2015 - nature.com
After the accident at the Fukushima Daiichi Nuclear Power Plant, the thyroid ultrasound
screening program for children aged 0–18 at the time of the accident was started from …

Molecular testing for oncogenic gene alterations in pediatric thyroid lesions

S Mostoufi-Moab, E Labourier, L Sullivan, V LiVolsi… - Thyroid, 2018 - liebertpub.com
Background: Thyroid nodules are less common in pediatric patients (ie, those≤ 18 years)
than they are in adults. The Bethesda System for Reporting Thyroid Cytopathology allows for …

Molecular genetics of thyroid cancer in children and adolescents

AJ Bauer - Endocrinology and Metabolism Clinics, 2017 - endo.theclinics.com
In the simplest approach, thyroid cancer is divided into 2 major categories: follicularderived
tumors, including follicular thyroid carcinoma (FTC) and papillary thyroid carcinoma (PTC) …

Mutational analysis in pediatric thyroid cancer and correlations with age, ethnicity, and clinical presentation

ME Nikita, W Jiang, SM Cheng, FM Hantash… - Thyroid, 2016 - liebertpub.com
Background: Well-differentiated thyroid cancer (WDTC) incidence in pediatrics is rising, most
being papillary thyroid carcinoma (PTC). The objective of the study was to assess the …

Pediatric, adolescent, and young adult thyroid carcinoma harbors frequent and diverse targetable genomic alterations, including kinase fusions

P Vanden Borre, AB Schrock, PM Anderson… - The …, 2017 - academic.oup.com
Background Thyroid carcinoma, which is rare in pediatric patients (age 0–18 years) but
more common in adolescent and young adult (AYA) patients (age 15–39 years), carries the …

Are we really at the dawn of understanding sporadic pediatric thyroid carcinoma?

MICV Cordioli, L Moraes, AN Cury… - Endocrine-related …, 2015 - erc.bioscientifica.com
Data from the National Cancer Institute and from the literature have disclosed an increasing
incidence of thyroid cancer in children, adolescents and adults. Although children and …