One of the lethal illnesses that humanity has ever seen is COVID-19 irrefutably. The speed of virus spread is high and happens through polluted surfaces, respiratory droplets, and …
Based on the structural study of previously known CDK2 inhibitors, a new series of pyrazolo [1, 5-a] pyrimidine derivatives was designed and synthesized. The target compounds were …
Abstract Novel 5-amino-1, 2, 4-triazole derivatives and their cyclized 1, 2, 4-triazolo [1, 5-a] pyrimidine analogues were designed, synthesized and evaluated for their antimicrobial …
Abstract Cu (II), Ni (II), Co (II) and Mn (II) chloro in addition to Cu (II) acetato complexes of the ligand termed 3-amino-4-(2-(3-chlorophenyl) hydrazono)-1H-pyrazol-5 (4H)-one …
Diverse new azoloazines were synthesized from the reaction of fluorinated hydrazonoyl chlorides with heterocyclic thiones, 1, 8‐diaminonaphthalene, ketene aminal derivatives …
The vascular endothelial growth factor receptor 2 (VEGFR2) is considered as a significant target for inhibition in the discovery of novel molecules with anti-proliferative activity. Here …
SF Mohamed, DH Elnaggar, MA Elsayed… - Polycyclic Aromatic …, 2023 - Taylor & Francis
A novel series of five or six new nitrogenated heterocyclic compounds were obtained by reacting a chalcone derivative of 3-acetylindole with various reagents such as malononitrile …
Divalent cobalt and copper chelates of the two ligands 1-(1-ethoxycarbonylmethyl-2- oxoindolin-3-ylidene) thiosemicarbazide (EOIT) and 1-(1-benzyl-2-oxoindolin-3-ylidene) …
A Bayazeed, NA Alenazi, AMR Alsaedi… - Journal of Molecular …, 2022 - Elsevier
In this article, we synthesized new formazan derivatives and they were evaluated for their antimicrobial activity and their minimum inhibitory concentration values against three gram …