Cellular senescence as a brake or accelerator for oncogenic transformation and role in lymphatic metastasis

P Banerjee, N Gaddam, TK Pandita… - International Journal of …, 2023 - mdpi.com
Cellular senescence—the irreversible cell cycle arrest driven by a variety of mechanisms
and, more specifically, the senescence-associated secretory phenotype (SASP)—is an …

The contribution of the meningeal immune interface to neuroinflammation in traumatic brain injury

AY Mokbel, MP Burns, BS Main - Journal of neuroinflammation, 2024 - Springer
Traumatic brain injury (TBI) is a major cause of disability and mortality worldwide,
particularly among the elderly, yet our mechanistic understanding of what renders the post …

Cranial Bone Changes Induced by Mild Traumatic Brain Injuries: A Neglected Player in Concussion Outcomes?

BD Semple, O Panagiotopoulou - Neurotrauma reports, 2023 - liebertpub.com
Mild traumatic brain injuries (TBIs), particularly when repetitive in nature, are increasingly
recognized to have a range of significant negative implications for brain health. Much of the …

[HTML][HTML] Inactivation of ERK1/2 signaling mediates dysfunction of basal meningeal lymphatic vessels in experimental subdural hematoma

J Yuan, X Liu, M Nie, Y Chen, M Liu, J Huang… - Theranostics, 2024 - ncbi.nlm.nih.gov
Abstract Rationale: Meningeal lymphatic vessels (MLVs) are essential for the clearance of
subdural hematoma (SDH). However, SDH impairs their drainage function, and the …

The Interplay between Meningeal Lymphatic Vessels and Neuroinflammation in Neurodegenerative Diseases

J Chen, Y Pan, Q Liu, G Li, G Chen, W Li… - Current …, 2024 - ingentaconnect.com
Meningeal lymphatic vessels (MLVs) are essential for the drainage of cerebrospinal fluid,
macromolecules, and immune cells in the central nervous system. They play critical roles in …

Amyloid beta-induced signalling in leptomeningeal cells and its impact on astrocyte response

M Abubaker, JE Stanton, O Mahon… - Molecular and Cellular …, 2024 - Springer
The pathological signature of Alzheimer's disease (AD) includes the accumulation of toxic
protein aggregates, mainly consisting of amyloid beta (Aβ). Recent strides in fundamental …

[PDF][PDF] 脑膜淋巴管重塑在中枢神经系统疾病中的研究进展

李建涛, 陈志毅, 齐淑雅, 黄青芸, 谭国鹤 - 生命科学, 2023 - lifescience.sinh.ac.cn
近年来, 随着脑膜淋巴管(meningeal lymphatic vessels, MLVs) 研究的进一步深入,
越来越多的证据表明MLVs 在中枢神经系统疾病的发生发展中扮演着重要角色 …

Comparative analysis of meningeal transcriptomes in birds: Potential pathways of resilience to repeated impacts

AE Beatty, TM Barnes‐Tompkins, KM Long… - The Anatomical … - Wiley Online Library
The meninges and associated vasculature (MAV) play a crucial role in maintaining cerebral
integrity and homeostasis. Recent advances in transcriptomic analysis have illuminated the …

Amyloid Beta–induced leptomeningeal cell JAK/STAT signalling regulates inflammatory responses of astrocytes in Alzheimer's Disease

M Abubaker, J Stanton, O Mahon, A Grabrucker… - 2024 - researchsquare.com
The pathological signature of Alzheimer's disease (AD) includes the accumulation of toxic
protein aggregates, mainly consisting of amyloid beta (Aβ). Recent strides in fundamental …

Cranial Bone Changes Induced by Mild Head Impacts: A Neglected Player in Concussion Outcomes?

B Semple, O Panagiotopoulou - 2023 - preprints.org
Mild impacts to the head, particularly when repetitive in nature, are increasingly recognized
to have a range of significant negative implications for brain health. Much of the ongoing …