Transposon mediated functional genomic screening for BRAF inhibitor resistance reveals convergent Hippo and MAPK pathway activation events
L Chen, I Pruteanu-Malinici, A Dastur, X Yin… - Scientific Reports, 2025 - nature.com
Genotype-informed anticancer therapies such as BRAF inhibitors can show remarkable
clinical efficacy in BRAF-mutant melanoma; however, drug resistance poses a major hurdle …
clinical efficacy in BRAF-mutant melanoma; however, drug resistance poses a major hurdle …