Polymeric nanoparticles for delivery of natural bioactive agents: recent advances and challenges

M Elmowafy, K Shalaby, MH Elkomy, OA Alsaidan… - Polymers, 2023 - mdpi.com
In the last few decades, several natural bioactive agents have been widely utilized in the
treatment and prevention of many diseases owing to their unique and versatile therapeutic …

Lipid-based nanoparticles in delivering bioactive compounds for improving therapeutic efficacy

P Patel, K Garala, S Singh, BG Prajapati… - Pharmaceuticals, 2024 - mdpi.com
In recent years, due to their distinctive and adaptable therapeutic effects, many natural
bioactive compounds have been commonly used to treat diseases. Their limited solubility …

Myricetin-loaded SBA-15 silica nanoparticles for enhanced management of pyrexia, pain, and inflammation through modulation of MAPK/NF-κB and COX-2/PGE-2 …

ZA El-Gendy, NM Ammar, AM Kassem, MS Attia… - International journal of …, 2024 - Elsevier
Myricetin (MYR) is a natural flavonoid that has several biological functions. However, some
of its beneficial effects are diminished due to low water solubility, stability, and …

[HTML][HTML] A pH-sensitive silica nanoparticles for colon-specific delivery and controlled release of catechin: Optimization of loading efficiency and in vitro release kinetics

AM Kassem, M Almukainzi, TM Faris, AH Ibrahim… - European Journal of …, 2024 - Elsevier
Catechin is a naturally occurring flavonoid of the flavan-3-ol subclass with numerous
biological functions; however, these benefits are diminished due to several factors, including …

Optimizing Etodolac and Quercetin Loaded MSNs Using Taguchi Design: An approach for Enhancing Drug Loading Efficiency

S Chougule, H Ahmed, S Singh, M Agrawal… - Journal of …, 2025 - Elsevier
The application of mesoporous silica nanoparticles (MSN) as a drug carrier system got
immense attention in the past few years due to their exceptional high drug loading efficiency …

Optimisation of albendazole delivery and assessment of anticancer potential in hepatocellular carcinoma (HepG2 cells) using surface modified nanostructured lipid …

W Anwar, AM Kassem, A Salama… - Journal of …, 2025 - Taylor & Francis
This study evaluated albendazole (ABZ) nanostructured lipid carriers (NLCs) for
hepatocellular carcinoma treatment. ABZ-NLCs were prepared using emulsification …

Improvement of the mechanical, rheological and bioadhesive properties of environmentally responsive systems containing different cellulose derivatives for quercetin …

G Furlan, JB da Silva, ML Bruschi - Materials Today Communications, 2025 - Elsevier
This study investigated polymeric blends of cellulose derivatives and poloxamer 407 as
thermoresponsive and bioadhesive systems for drug delivery, with focus on the topical …

Polymorph transformation of solid drugs and inhibiting strategies

Y Feng, H Wang, D Wu, K Chen, N Wang, T Wang… - …, 2024 - pubs.rsc.org
Metastable forms and amorphous forms exhibit higher solubility and dissolution rates
compared to stable crystalline forms, making them viable options for pharmaceuticals with …

Enhancing the inhibition of dental erosion and abrasion with quercetin-encapsulated hollow mesoporous silica nanocomposites

JM Chen, YL Cheng, MH Yang, C Su… - … in Bioengineering and …, 2024 - frontiersin.org
Introduction: Dental erosion and abrasion pose significant clinical challenges, often leading
to exposed dentinal tubules and dentine demineralization. The aim of this study was to …

Intensification of Quercetin Nanobubble Formulation and Performance by Multi-Factor Optimization and Interaction Analysis

H Kumar AV, C Kantlam - Pharmaceutical Development and …, 2024 - Taylor & Francis
The natural flavonoid Quercetin (QT) showed a potential for various health benefits, but its
pharmaceutical applications are hindered by low solubility, permeability, and limited …