A limited number of tissues can spontaneously regenerate following injury, and even fewer
can regenerate to a state comparable to mature, healthy adult tissue. Mesenchymal stem …

Abstract This" Year in Review" presents a curated selection of research themes and
individual studies within the clinical osteoarthritis (OA) field, focusing on epidemiology and …

Introduction: Knee osteoarthritis (OA) is a common degenerative joint condition and a major
cause of disability in the general population. Source of data: Recent published literature …

Remarkable advancements have been made in understanding the pathogenesis of
Alzheimer's disease, Parkinson's disease, and other neurological disease; in our depth of …

Purpose Injectable biologics have not only been described and developed to treat dermal
wounds, cardiovascular disease, and cancer, but have also been reported to treat chronic …

Process models are a growing tool for pharmaceutical manufacturing process design and
control. The Industry 4.0 paradigm promises to increase the amount of data available to …

Advanced therapies are expected to play a crucial role in supporting repair after injury,
halting the degeneration of musculoskeletal tissue to enable and promote physical activity …

Osteoarthritis (OA) is the most common disease in aging joints and has characteristics of
cartilage destruction and inflammation. It is currently considered a metabolic disease, and …

Background The comorbidity of chronic pancreatitis (CP) in patients with osteoarthritis (OA)
is insufficiently studied, and the reciprocal impact of these conditions remains poorly …

Objectives To assess the efficacy of a single intradiscal injection of allogeneic bone marrow
mesenchymal stromal cells (BM-MSCs) versus a sham placebo in patients with chronic low …