Synergistic chemotherapy and phototherapy based on red blood cell biomimetic nanomaterials

D Meng, S Yang, Y Yang, L Zhang, L Cui - Journal of Controlled Release, 2022 - Elsevier
Novel drug delivery systems (DDSs) have become the mainstay of research in targeted
cancer therapy. By combining different therapeutic strategies, potential DDSs and …

Targeted implementation strategies of precise photodynamic therapy based on clinical and technical demands

Y Qian, J Wang, W Bu, X Zhu, P Zhang, Y Zhu… - Biomaterials …, 2023 - pubs.rsc.org
With the development of materials science, photodynamic-based treatments have gradually
entered clinics. Photodynamic therapy is ideal for cancer treatment due to its non-invasive …

Design and biological evaluation of lipoprotein-based donepezil nanocarrier for enhanced brain uptake through oral delivery

KV Krishna, G Wadhwa, A Alexander… - ACS chemical …, 2019 - ACS Publications
Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
memory and cognitive impairment. Donepezil is an acetylcholinesterase inhibitor used for …

Fluorescence-based method for sensitive and rapid estimation of chlorin e6 in stealth liposomes for photodynamic therapy against cancer

R Jain, R Pradhan, S Hejmady, G Singhvi… - Spectrochimica Acta Part …, 2021 - Elsevier
Chlorin e6 is a chlorine-based porphyrin containing photosensitizer mainly used for the
therapy in cancers like neck and head, early-stage lung cancer, and topical skin cancers …

Reviewing the evolutive ACQ‐to‐AIE transformation of photosensitizers for phototheranostics

W Zhu, L Huang, C Wu, L Liu, H Li - Luminescence, 2024 - Wiley Online Library
Photodynamic therapy (PDT) represents an emerging noninvasive treatment technique for
cancers and various nonmalignant diseases, including infections. During the process of …

Sensitizers in photodynamic therapy

S Parab, PK Achalla, N Yanamandala, G Singhvi… - Nanomaterials for …, 2023 - Elsevier
Photodynamic therapy (PDT) is a treatment method, based on taking advantage of the
reactive oxygen species generated by irradiation of photosensitizers (PSs). Among various …

Stability indicating validated high‐performance liquid chromatography method for simultaneous estimation of chlorin e6 and curcumin in bulk and drug‐loaded lipidic …

R Jain, SK Dubey, G Singhvi - Separation Science Plus, 2023 - Wiley Online Library
Chlorin e6 and curcumin are often used in the treatment of various cancers, including breast,
skin, colon, and lung cancer. The present objective of this study is to develop a simple …

Development and validation of a stability‐indicating reversed‐phase–high‐performance liquid chromatography method for quantification of 2‐[1‐hexyloxyethyl]‐2 …

R Pradhan, SK Dubey, A Puri… - Separation Science …, 2023 - Wiley Online Library
[1‐hexyloxyethyl]‐2‐devinyl pyropheophorbide‐a is a second‐generation, lipophilic, chlorin‐
based photosensitizer currently used for various types of solid cancer including breast …

A novel UPLC–MS/MS method for simultaneous quantification of trigonelline, 4‐hydroxyisoleucine, and diosgenin from Trigonella foenum‐graecum extract …

G Wadhwa, KV Krishna, R Taliyan… - Biomedical …, 2022 - Wiley Online Library
Abstract Trigonelline (TR), 4‐hydroxyisoleucine (4‐HI), and diosgenin (DG) are the main
bioactives of the purified standardized extract of the popular plant Trigonella foenum …

Preparation, characterization and pharmacokinetic study of N-terminal PEGylated D-form antimicrobial peptide OM19r-8

Q Cui, Q Xu, L Liu, L Guan, X Jiang, M Inam… - Journal of …, 2021 - Elsevier
Recently, new cationic antibacterial peptide OM19R has been designed with low minimum
inhibitory concentration (MIC) values against some gram-negative bacteria, such as …