The inflammatory process plays a significant role in the development of colon cancer (CRC).
Intestinal cytokine networks are critical mediators of tissue homeostasis and inflammation …

In inflammatory bowel disease (IBD), chronic inflammation in the gastrointestinal tract can
lead to tissue damage and remodelling, which can ultimately result in fibrosis. Prolonged …

Crohn's disease (CD) is a type of inflammatory bowel disease (IBD) that manifests mainly as
chronic inflammation in different parts of the gastrointestinal tract, and its incidence has …

Background and aims The stiffening of the extracellular matrix, and changes in its cellular
and molecular composition, have been reported in the pathogenesis of fibrosis. We analyze …

Chronic inflammation is often associated with fibrotic disorders in which an excessive
deposition of extracellular matrix is a hallmark. Long-term fibrosis starts with tissue …

Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic, and ultimately fatal diffuse
parenchymal lung disease. The molecular mechanisms of fibrosis in IPF patients are not …

Tropomyosin 4 (TPM4) has been reported as an oncogenic gene across different
malignancies. However, the role of TPM4 in glioma remains unclear. This study aimed to …

The epithelial–mesenchymal transition (EMT) is closely associated with Crohn's disease
(CD) related intestinal fibrosis, a condition whose prevalence is increasing annually among …

Periodontitis, a common oral disease characterized by the progressive infiltration of bacteria,
is a leading cause of adult tooth loss. Periodontal stem cells (PDLSCs) possess good self …

Background and aims: The stiffening of the extracellular matrix, and changes in its cellular
and molecular composition, have been reported in the pathogenesis of fibrosis. We analyze …