Platelet-derived growth factor (PDGF) isoforms and PDGF receptors have important
functions in the regulation of growth and survival of certain cell types during embryonal …

Platelet‐derived growth factor (PDGF) isoforms and their receptors have important roles
during embryogenesis, particularly in the development of various mesenchymal cell types in …

Imatinib inhibits the activity of several tyrosine kinases, including BCR-ABL, KIT and platelet-
derived growth factor receptor (PDGFR). Dysregulation of KIT is found in mast cell tumours …

Human angiosarcoma and canine hemangiosarcoma reveal similarities not only in their
aggressive clinical behaviour, but especially in molecular landscape and genetic alterations …

Canine malignant melanoma (CMM) is the most common canine oral tumour, and up to 70–
75% of dogs in stage II–III die within 1 year after surgery. The purpose of this study was to …

Objectives To investigate thalidomide as an adjuvant treatment for canine
haemangiosarcoma. Materials and Methods Fifteen dogs with splenic haemangiosarcoma …

Canine perivascular wall tumors (PWTs) are a group of subcutaneous soft tissue sarcomas
developing from vascular mural cells. Mural cells are involved in angiogenesis through a …

Background Canine oral fibrosarcoma (COF) is one of the most common oral tumors in dogs
and carries a guarded prognosis due to a lack of effective systemic therapeutic options …

Canine tumors are valuable comparative models for human counterparts, especially to
explore novel biomarkers and to understand pathways and processes involved in …

Canine haemangiosarcoma (HSA), like human angiosarcoma, is an uncommon malignant
vascular endothelial cell tumour associated with a poor prognosis. The peroxiredoxin …