SIRT1 in neurodevelopment and brain senescence

AZ Herskovits, L Guarente - Neuron, 2014 - cell.com
Sirtuins are nicotinamide adenine dinucleotide (NAD+)-dependent deacylases that have
traditionally been linked with calorie restriction and aging in mammals. These proteins also …

Therapeutic potential of resveratrol: the in vivo evidence

JA Baur, DA Sinclair - Nature reviews Drug discovery, 2006 - nature.com
Resveratrol, a constituent of red wine, has long been suspected to have cardioprotective
effects. Interest in this compound has been renewed in recent years, first from its …

[引用][C] Herbal medicine: biomolecular and clinical aspects

IFF Benzie - 2011 - books.google.com
Responding to the increased popularity of herbal medicines and other forms of
complementary or alternative medicine world-wide, this reference reviews and evaluates …

Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism

Y Porat, A Abramowitz, E Gazit - Chemical biology & drug …, 2006 - Wiley Online Library
The formation of well‐ordered fibrillar protein deposits is common to a large group of
amyloid‐associated disorders. This group consists of several major human diseases such …

Polyphenolic compounds and digestive enzymes: In vitro non-covalent interactions

AI Martinez-Gonzalez, ÁG Díaz-Sánchez… - Molecules, 2017 - mdpi.com
The digestive enzymes–polyphenolic compounds (PCs) interactions behind the inhibition of
these enzymes have not been completely studied. The existing studies have mainly …

Bioactive compounds in wine: Resveratrol, hydroxytyrosol and melatonin: A review

MI Fernández-Mar, R Mateos, MC Garcia-Parrilla… - Food chemistry, 2012 - Elsevier
Regular moderate wine consumption is often associated with reduced morbidity and
mortality from a variety of chronic diseases in which inflammation is the root cause. This …

Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets

C Ramassamy - European journal of pharmacology, 2006 - Elsevier
Aging is the major risk factor for neurodegenerative diseases such as Alzheimer's and
Parkinson's diseases. A large body of evidence indicates that oxidative stress is involved in …

Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment

R Krikorian, TA Nash, MD Shidler… - British journal of …, 2010 - cambridge.org
Concord grape juice contains polyphenol compounds, which have antioxidant and anti-
inflammatory properties and influence neuronal signalling. Concord grape juice …

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease

SS Karuppagounder, JT Pinto, H Xu, HL Chen… - Neurochemistry …, 2009 - Elsevier
Resveratrol, a polyphenol found in red wine, peanuts, soy beans, and pomegranates,
possesses a wide range of biological effects. Since resveratrol's properties seem ideal for …

Preconditioning is hormesis part I: Documentation, dose-response features and mechanistic foundations

EJ Calabrese - Pharmacological Research, 2016 - Elsevier
This article provides the first extensive documentation of the dose response features of pre-
and postconditioning. Pre-and postconditioning studies with rigorous study designs, using …