Saliva and oral diseases

E Martina, A Campanati, F Diotallevi… - Journal of clinical …, 2020 - mdpi.com
Saliva is a fascinating biological fluid which has all the features of a perfect diagnostic tool.
In fact, its collection is rapid, simple, and noninvasive. Thanks to several transport …

Advancing cancer detection with portable salivary sialic acid testing

M Elgendi, L Lyzwinski, E Kübler, AV Shokurov… - npj Biosensing, 2024 - nature.com
This perspective emphasizes the robust evidence supporting salivary sialic acid (SA) as a
valuable tool for cancer prescreening, particularly for oral and breast cancers. The potential …

[HTML][HTML] Potential role of nuclear magnetic resonance spectroscopy to identify salivary metabolite alterations in patients with head and neck cancer

JJW Mikkonen, SP Singh, R Akhi, T Salo… - Oncology …, 2018 - spandidos-publications.com
The analysis of the salivary metabolomic profile may offer an early phase approach to
assess the changes associated with a wide range of diseases including head and neck …

Verification of saliva matrix metalloproteinase-1 as a strong diagnostic marker of oral cavity cancer

YT Chang, LJ Chu, YC Liu, CJ Chen, SF Wu, CH Chen… - Cancers, 2020 - mdpi.com
Oral squamous cell carcinoma (OSCC) accounts for> 90% of cases of oral cancer, including
cancer at the lip and oral cavity and cancer at the oropharynx. Most OSCCs develop from …

[HTML][HTML] Elevated serum sialic acid levels predict prostate cancer as well as bone metastases

C Zhang, L Yan, H Song, Z Ma, D Chen, F Yang… - Journal of …, 2019 - ncbi.nlm.nih.gov
Objective: To evaluate the value of serum sialic acid (SA) in diagnosis of benign prostatic
hyperplasia (BPH), prostate cancer (PCa), and bone metastases in PCa patients. Materials …

[HTML][HTML] Clinical validation of a saliva-based matrix metalloproteinase-1 rapid strip test for detection of oral cavity cancer

LJ Chu, YT Chang, CY Chien, HC Chung, SF Wu… - Biomedical Journal, 2024 - Elsevier
Background We previously identified matrix metalloproteinase-1 (MMP-1) as one of the most
promising salivary biomarkers for oral squamous cell carcinoma (OSCC) and developed a …

Protein glycosylation in head and neck cancers: From diagnosis to treatment

M Rasheduzzaman, A Kulasinghe, R Dolcetti… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Glycosylation is the most common post-translational modification (PTM) of proteins.
Malignant tumour cells frequently undergo an alteration in surface protein glycosylation. This …

Sialic acid content in human saliva and anti-influenza activity against human and avian influenza viruses

N Limsuwat, O Suptawiwat, C Boonarkart… - Archives of …, 2016 - Springer
It was shown previously that human saliva has higher antiviral activity against human
influenza viruses than against H5N1 highly pathogenic avian influenza viruses, and that the …

Salivary biomarkers in oral cancer

P Panta, DTW Wong - Oral Cancer Detection: Novel Strategies and Clinical …, 2019 - Springer
Saliva is an easily accessible biofluid with immense diagnostic potential in oral cancer. The
identification of potential saliva signatures for early, noninvasive detection of oral squamous …

A non-invasive study to estimate and compare salivary sialic acid level as tumor marker in patients with pre-cancer and oral cancer

TV Jacob, M Ramesh, S Murali, K Ramesh… - Journal of cancer …, 2016 - journals.lww.com
Materials and Methods: Samples of 2 ml of unstimulated whole saliva were collected from 20
healthy patients, and 20 cases of histopathologically confirmed oral pre-cancer patients and …