This review covers recent advances in understanding the molecular mechanisms controlling
neurogenesis and specification of the developing retina, with a focus on insights obtained …

Across the animal kingdom, visual systems have evolved to be uniquely suited to the
environments and behavioral patterns of different species. Visual acuity and color …

Non-mammalian vertebrates have a robust ability to regenerate injured retinal neurons from
Müller glia (MG) that activate the gene encoding the proneural factor Achaete-scute …

Previous studies have shown that Müller glia are closely related to retinal progenitors; these
two cell types express many of the same genes and after damage to the retina, Müller glia …

Retinoblastoma is a rare childhood cancer of the developing retina. Most retinoblastomas
initiate with biallelic inactivation of the RB1 gene through diverse mechanisms including …

During vertebrate retinal development, subsets of progenitor cells generate progeny in a
non-stochastic manner, suggesting that these decisions are tightly regulated. However, the …

Diseases and damage to the retina lead to losses in retinal neurons and eventual visual
impairment. Although the mammalian retina has no inherent regenerative capabilities, fish …

Epigenetic regulation of the genome is critical for the emergence of diverse cell lineages
during development. To understand the role of DNA methylation during retinal network …

The homeoprotein family comprises~ 300 transcription factors and was long seen as
primarily involved in developmental programs through cell autonomous regulation …

During development, neural progenitors change their competence states over time to
sequentially generate different types of neurons and glia. Several cascades of temporal …