Evidence for the gut microbiota short‐chain fatty acids as key pathophysiological molecules improving diabetes

A Puddu, R Sanguineti, F Montecucco… - Mediators of …, 2014 - Wiley Online Library
In type 2 diabetes, hyperglycemia, insulin resistance, increased inflammation, and oxidative
stress were shown to be associated with the progressive deterioration of beta‐cell function …

Coordination of social behaviors by the bed nucleus of the stria terminalis

ME Flanigan, TL Kash - European Journal of Neuroscience, 2022 - Wiley Online Library
The bed nucleus of the stria terminalis (BNST) is a sexually dimorphic, neuropeptide‐rich
node of the extended amygdala that has been implicated in responses to stress, drugs of …

Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior

JG McCall, ER Siuda, DL Bhatti, LA Lawson… - Elife, 2017 - elifesciences.org
Increased tonic activity of locus coeruleus noradrenergic (LC-NE) neurons induces anxiety-
like and aversive behavior. While some information is known about the afferent circuitry that …

Comprehensive mapping of neurotransmitter networks by MALDI–MS imaging

M Shariatgorji, A Nilsson, E Fridjonsdottir… - Nature …, 2019 - nature.com
We present a mass spectrometry imaging (MSI) approach for the comprehensive mapping of
neurotransmitter networks in specific brain regions. Our fluoromethylpyridinium-based …

In vivo ambient serotonin measurements at carbon-fiber microelectrodes

A Abdalla, CW Atcherley, P Pathirathna… - Analytical …, 2017 - ACS Publications
The mechanisms that control extracellular serotonin levels in vivo are not well-defined. This
shortcoming makes it very challenging to diagnose and treat the many psychiatric disorders …

Carbon nanotube yarn electrodes for enhanced detection of neurotransmitter dynamics in live brain tissue

AC Schmidt, X Wang, Y Zhu, LA Sombers - ACS nano, 2013 - ACS Publications
This work demonstrates the potential of nanoscale carbon electrode materials for improved
detection of electroactive neurotransmitter dynamics in the brain. Individual multiwalled …

[HTML][HTML] Neuropeptide regulation of signaling and behavior in the BNST

TL Kash, KE Pleil, CA Marcinkiewcz… - Molecules and cells, 2015 - Elsevier
Recent technical developments have transformed how neuroscientists can probe brain
function. What was once thought to be difficult and perhaps impossible, stimulating a single …

Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo

M Dunn, A Henke, S Clark, Y Kovalyova… - Nature …, 2018 - nature.com
Norepinephrine is a monoamine neurotransmitter with a wide repertoire of physiological
roles in the peripheral and central nervous systems. There are, however, no experimental …

Dorsal BNST α2A-adrenergic receptors produce HCN-dependent excitatory actions that initiate anxiogenic behaviors

NA Harris, AT Isaac, A Günther, K Merkel… - Journal of …, 2018 - Soc Neuroscience
Stress is a precipitating agent in neuropsychiatric disease and initiates relapse to drug-
seeking behavior in addicted patients. Targeting the stress system in protracted abstinence …

Corticotropin releasing factor and norepinephrine related circuitry changes in the bed nucleus of the stria terminalis in stress and alcohol and substance use disorders

AE Snyder, Y Silberman - Neuropharmacology, 2021 - Elsevier
Abstract Alcohol Use Disorder (AUD) affects around 14.5 million individuals in the United
States, with Substance Use Disorder (SUD) affecting an additional 8.3 million individuals …