In Positron Emission Tomography (PET), spectral analysis (SA) allows the quantification of
dynamic data by relating the radioactivity measured by the scanner in time to the underlying …

Application of metabolic magnetic resonance imaging measures such as cerebral blood flow
in translational medicine is limited by the unknown link of observed alterations to specific …

A loss of GABA signaling is a prevailing hypothesis for the pathogenesis of schizophrenia.
Preclinical studies indicate that blockade of the α5 subtype of the GABA receptor (α5 …

High-frequency oscillations in the gamma-band reflect rhythmic synchronization of spike
timing in active neural networks. The modulation of gamma oscillations is a widely …

GABA (gamma-amino-butyric-acid) is the primary inhibitory neurotransmitter in the human
brain. It has been proposed that the symptoms of autism spectrum disorders (ASDs) are the …

Frontotemporal dysconnectivity is a key pathology in schizophrenia. The specific nature of
this dysconnectivity is unknown, but animal models imply dysfunctional theta phase coupling …

Preliminary studies have suggested that γ-aminobutyric acid type A (GABAA) receptors, and
potentially the GABAA α5 subtype, are deficient in autism spectrum disorder (ASD) …

Positron emission tomography (PET) neuroimaging of ion channel linked receptors is a
developing area of preclinical and clinical research. The present review focuses on recent …

Placing a patient in a state of anaesthesia is crucial for modern surgical practice. However,
the mechanisms by which anaesthetic drugs, such as propofol, impart their effects on …

Neuronal inhibition, primarily mediated by GABAergic neurotransmission, is crucial for brain
development and healthy cognition. Gamma-aminobutyric acid concentration levels in …