An mRNA transcript that codes for a Disintegrin and a Metalloprotease from a venom gland of the viper Bothrops ammodytoides was isolated. Vector pCR® 2.1-TOPO was used to …
Bothrops asper is one of the most important snake species in Central America, mainly because of its medical importance in countries like Ecuador, Panama and Costa Rica …
Phospholipase A2 (PLA2) toxins are one of the main toxin families found in snake venom. PLA2 toxins are associated with various detrimental effects, including neurotoxicity …
ZM Yang, Q Guo, ZR Ma, Y Chen, ZZ Wang… - Journal of …, 2015 - Elsevier
The cDNAs encoding four major phospholipases A 2 (PLA 2 s) were sequenced while the expressed sequence tags of Gloydius intermedius venom glands were constructed. These …
Abstract Phospholipases A 2 (PLA 2 s) constitute a class of extensively studied toxins, isolated from snake venoms. Basic PLA 2 isoforms mediate various toxicological effects …
A mRNA transcript that codes for a phospholipase (PLA 2) was isolated from a single venom gland of the Bothrops ammodytoides viper. The PLA 2 transcript was cloned onto a pCR® …
This study aimed to elucidate anticoagulant/antiplatelet mechanisms of two previously purified PLA2s from Cerastes cerastes venom, here, termed Cc1‐PLA2 and Cc2‐PLA2. Both …
Bothropic venoms contain enzymes such as metalloproteases, serine-proteases, and phospholipases, which acting by themselves, or in synergism, are the cause of the …
PI Regner, MD Saggese, VC de Oliveira, LC Lanari… - Toxicon, 2022 - Elsevier
Several species of reptiles and mammals have components in their sera that can neutralize toxic components present in snake venoms. In this manuscript, we studied the neutralizing …