Overdosing with methadone is a growing phenomenon in Britain and other countries due to
the increase in prescription and the availability of this compound. Little is known of the …

This review provides a brief overview on chirality as a structural characteristic of
pharmaceuticals. This property has received very little attention in the field of environmental …

The aim of this study was to evaluate the performance of a technique for simultaneous
testing of hydrophilic abuse drugs in hair. The analysis of, codeine and methadone in …

Aim To construct a population pharmacokinetic model for methadone enantiomers in the
setting of methadone maintenance treatment for opioid dependence. Methods A population …

The electrochemical sensor was developed for determination of methadone (MTD) using
multi‐walled carbon nanotubes (MWCNT) modified pencil graphite electrode (MWCNT …

Racemic methadone (MET) is administered to heroin users undergoing methadone
maintenance therapy (MMT) in Australia. The enantiomers of methadone possess different …

A high-throughput method for quantitative determination of methadone enantiomers in
human plasma was developed and validated by liquid chromatography/tandem mass …

Purpose. A combined microextraction and separation method is presented for the
determination of methadone in exhaled breath condensate (EBC) which is a promising non …

Background: As the pharmacokinetics of methadone exhibit large inter-subject variability,
providing a simple and reliable analytical method for the monitoring of methadone levels in …

Methadone and buprenorphine are two of the drugs most frequently used for abstinence
from illicit opioids and in the treatment of pain. A sensitive and selective high-performance …