Mechanisms of the acute effects of inhaled ozone in humans

PA Bromberg - Biochimica et Biophysica Acta (BBA)-General Subjects, 2016 - Elsevier
Ambient air ozone (O 3) is generated photochemically from oxides of nitrogen and volatile
hydrocarbons. Inhaled O 3 causes remarkably reversible acute lung function changes and …

Possible molecular mechanisms linking air pollution and asthma in children

S Esposito, R Tenconi, M Lelii, V Preti, E Nazzari… - BMC pulmonary …, 2014 - Springer
Background Air pollution has many effects on the health of both adults and children, but
children's vulnerability is unique. The aim of this review is to discuss the possible molecular …

Lung function and inflammatory responses in healthy young adults exposed to 0.06 ppm ozone for 6.6 hours

CS Kim, NE Alexis, AG Rappold, H Kehrl… - American journal of …, 2011 - atsjournals.org
Rationale: Exposure to ozone causes a decrease in spirometric lung function and an
increase in airway inflammation in healthy young adults at concentrations as low as 0.08 …

An update on immunologic mechanisms in the respiratory mucosa in response to air pollutants

RD Huff, C Carlsten, JA Hirota - Journal of allergy and clinical immunology, 2019 - Elsevier
Every day, we breathe in more than 10,000 L of air that contains a variety of air pollutants
that can pose negative consequences to lung health. The respiratory mucosa formed by the …

[HTML][HTML] Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility?

C van de Wetering, E Elko, M Berg, CHJ Schiffers… - Redox Biology, 2021 - Elsevier
Our lungs are exposed daily to airborne pollutants, particulate matter, pathogens as well as
lung allergens and irritants. Exposure to these substances can lead to inflammatory …

Assessing the impact of air pollution on childhood asthma morbidity: how, when, and what to do

AJ Burbank, DB Peden - Current opinion in allergy and clinical …, 2018 - journals.lww.com
Assessing the impact of air pollution on childhood asthma mo... : Current Opinion in Allergy and
Clinical Immunology Assessing the impact of air pollution on childhood asthma morbidity: how …

IL-1 receptor antagonist reduces endotoxin-induced airway inflammation in healthy volunteers

ML Hernandez, K Mills, M Almond, K Todoric… - Journal of Allergy and …, 2015 - Elsevier
Background Asthma with neutrophil predominance is challenging to treat with
corticosteroids. Novel treatment options for asthma include those that target innate immune …

Glutathione redox control of asthma: from molecular mechanisms to therapeutic opportunities

AM Fitzpatrick, DP Jones, LAS Brown - Antioxidants & redox …, 2012 - liebertpub.com
Asthma is a chronic inflammatory disorder of the airways associated with airway hyper-
responsiveness and airflow limitation in response to specific triggers. Whereas inflammation …

The effect of environmental oxidative stress on airway inflammation

A Auerbach, ML Hernandez - Current Opinion in Allergy and …, 2012 - journals.lww.com
Air pollution plays a critical role in asthma and may affect certain patients more than others.
Further investigation into the genetic polymorphisms that affect inflammatory responses may …

Respiratory responses to ozone exposure. Moses (the multicenter ozone study in older subjects)

M Arjomandi, JR Balmes, MW Frampton… - American journal of …, 2018 - atsjournals.org
Rationale: Acute respiratory effects of low-level ozone exposure are not well defined in older
adults. Objectives: MOSES (The Multicenter Ozone Study in Older Subjects), although …