Targeting the achilles heel of FtsZ: The interdomain cleft
Widespread antimicrobial resistance among bacterial pathogens is a serious threat to public
health. Thus, identification of new targets and development of new antibacterial agents are …
health. Thus, identification of new targets and development of new antibacterial agents are …
Models versus pathogens: how conserved is the FtsZ in bacteria?
Combating anti-microbial resistance by developing alternative strategies is the need of the
hour. Cell division, particularly FtsZ, is being extensively studied for its potential as an …
hour. Cell division, particularly FtsZ, is being extensively studied for its potential as an …
An adamantyl-caffeoyl-anilide exhibits broad-spectrum antibacterial activity by inhibiting FtsZ assembly and Z-ring formation
Several harmful bacteria have evolved resistance to conventional antibiotics due to their
extensive usage. FtsZ, a principal bacterial cell division protein, is considered as an …
extensive usage. FtsZ, a principal bacterial cell division protein, is considered as an …
Inhibition of Filamentous Thermosensitive Mutant-Z Protein in Bacillus subtilis by Cyanobacterial Bioactive Compounds
Antibiotic resistance is one of the major growing concerns for public health. Conventional
antibiotics act on a few predefined targets and, with time, several bacteria have developed …
antibiotics act on a few predefined targets and, with time, several bacteria have developed …
Filamentous thermosensitive mutant Z: An appealing target for emerging pathogens and a Trek on its natural inhibitors
Simple Summary Antimicrobial resistance (AMR) is a pressing issue worldwide that must be
addressed swiftly. It is driven by spontaneous evolution, bacterial mutation, and the …
addressed swiftly. It is driven by spontaneous evolution, bacterial mutation, and the …
Regulation of Streptococcus pneumoniae FtsZ assembly by divalent cations: paradoxical effects of Ca2+ on the nucleation and bundling of FtsZ polymers
The assembly and disassembly of the FtsZ ring drives the division of bacteria cells, including
Streptococcus pneumoniae, which causes pneumonia and meningitis. In contrast to FtsZ …
Streptococcus pneumoniae, which causes pneumonia and meningitis. In contrast to FtsZ …
Mechanistic insight into the effect of BT‐benzo‐29 on the Z‐ring in Bacillus subtilis
K Kunal, R Tiwari, HPS Dhaked, A Surolia… - IUBMB life, 2020 - Wiley Online Library
The assembly and disassembly of FtsZ play an essential role in bacterial cell division. Using
single‐cell imaging, we report that short exposure to BT‐benzo‐29 inhibits Z‐ring formation …
single‐cell imaging, we report that short exposure to BT‐benzo‐29 inhibits Z‐ring formation …
[PDF][PDF] Filamentous Thermosensitive Mutant Z: An Appealing Target for Emerging Pathogens and a Trek on Its Natural Inhibitors. Biology 2022, 11, 624
Antibiotic resistance is a major emerging issue in the health care sector, as highlighted by
the WHO. Filamentous Thermosensitive mutant Z (Fts-Z) is gaining significant attention in the …
the WHO. Filamentous Thermosensitive mutant Z (Fts-Z) is gaining significant attention in the …
Unique biochemical features of the cytokinetic protein FtsZ of Mycobacteria
P Gupta, A Pradhan, P Ajitkumar - Mycobacterium-Research and …, 2017 - books.google.com
FtsZ, the bacterial cytokinetic protein, a structural homologue of mammalian β-tubulin, is
present in bacteria of diverse genera, including mycobacteria. The FtsZ protein of …
present in bacteria of diverse genera, including mycobacteria. The FtsZ protein of …
Probing self-association of CetZ1 cytoskeletal protein from Haloferax volcanii
VD Shinde - 2021 - opus.lib.uts.edu.au
The cytoskeleton is a dynamic network of proteins, which are required by all cells for cell
division, growth, and maintenance of cell shape. A major group of cytoskeleton proteins …
division, growth, and maintenance of cell shape. A major group of cytoskeleton proteins …