The molecular mechanisms by which vitamin D prevents insulin resistance and associated disorders

I Szymczak-Pajor, J Drzewoski, A Śliwińska - International journal of …, 2020 - mdpi.com
Numerous studies have shown that vitamin D deficiency is very common in modern societies
and is perceived as an important risk factor in the development of insulin resistance and …

[HTML][HTML] Vitamin D metabolism, mechanism of action, and clinical applications

DD Bikle - Chemistry & biology, 2014 - cell.com
Vitamin D 3 is made in the skin from 7-dehydrocholesterol under the influence of UV light.
Vitamin D 2 (ergocalciferol) is derived from the plant sterol ergosterol. Vitamin D is …

Associations of vitamin D with insulin resistance, obesity, type 2 diabetes, and metabolic syndrome

SJ Wimalawansa - The Journal of steroid biochemistry and molecular …, 2018 - Elsevier
The aim of this study is to determine the relationships of vitamin D with diabetes, insulin
resistance obesity, and metabolic syndrome. Intra cellular vitamin D receptors and the 1-α …

Vitamin D deficiency and diabetes

MJ Berridge - Biochemical Journal, 2017 - portlandpress.com
Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the
role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β …

Physiological functions of Vitamin D in adipose tissue

MA Abbas - The Journal of steroid biochemistry and molecular …, 2017 - Elsevier
Adipose tissue has long been identified as the major site of vitamin D storage. Recent
studies have demonstrated that VDR and vitamin D metabolizing enzymes are expressed in …

The action of vitamin D in adipose tissue: is there the link between vitamin D deficiency and adipose tissue-related metabolic disorders?

I Szymczak-Pajor, K Miazek, A Selmi… - International Journal of …, 2022 - mdpi.com
Adipose tissue plays an important role in systemic metabolism via the secretion of
adipocytokines and storing and releasing energy. In obesity, adipose tissue becomes …

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

KS Vimaleswaran, DJ Berry, C Lu, E Tikkanen… - PLoS …, 2013 - journals.plos.org
Background Obesity is associated with vitamin D deficiency, and both are areas of active
public health concern. We explored the causality and direction of the relationship between …

The nonskeletal effects of vitamin D: an Endocrine Society scientific statement

CJ Rosen, JS Adams, DD Bikle, DM Black… - Endocrine …, 2012 - academic.oup.com
Significant controversy has emerged over the last decade concerning the effects of vitamin D
on skeletal and nonskeletal tissues. The demonstration that the vitamin D receptor is …

The relationship between obesity and serum 1, 25-dihydroxy vitamin D concentrations in healthy adults

SJ Parikh, M Edelman, GI Uwaifo… - The Journal of …, 2004 - academic.oup.com
Several previous reports of small cohorts have found significantly higher serum 1, 25-
dihydroxy vitamin D (1, 25-vit D) in obese compared with nonobese whites. Based on these …

Functional properties of whey, whey components, and essential amino acids: mechanisms underlying health benefits for active people

E Ha, MB Zemel - The Journal of nutritional biochemistry, 2003 - Elsevier
Whey proteins and amino acid supplements have a strong position in the sports nutrition
market based on the purported quality of proteins and amino acids they provide. Recent …