[HTML][HTML] Recent advances in using liposomes for delivery of nucleic acid-based therapeutics
Nucleic acid therapeutics are rapidly expanding because of recent advancements in
production and purification. This class of therapeutics may change the field of disease …
production and purification. This class of therapeutics may change the field of disease …
Drug delivery systems: Advanced technologies potentially applicable in personalized treatments
Advanced drug delivery systems (DDS) present indubitable benefits for drug administration.
Over the past three decades, new approaches have been suggested for the development of …
Over the past three decades, new approaches have been suggested for the development of …
Engineering stem cells to produce exosomes with enhanced bone regeneration effects: an alternative strategy for gene therapy
Background Exosomes derived from stem cells have been widely studied for promoting
regeneration and reconstruction of multiple tissues as “cell-free” therapies. However, the …
regeneration and reconstruction of multiple tissues as “cell-free” therapies. However, the …
Non-viral gene delivery systems for tissue repair and regeneration
P Wu, H Chen, R Jin, T Weng, JK Ho, C You… - Journal of translational …, 2018 - Springer
Critical tissue defects frequently result from trauma, burns, chronic wounds and/or surgery.
The ideal treatment for such tissue loss is autografting, but donor sites are often limited …
The ideal treatment for such tissue loss is autografting, but donor sites are often limited …
Biomaterial-assisted local and systemic delivery of bioactive agents for bone repair
Y Zeng, J Hoque, S Varghese - Acta biomaterialia, 2019 - Elsevier
Although bone tissues possess an intrinsic capacity for repair, there are cases where bone
healing is either impaired or insufficient, such as fracture non-union, osteoporosis …
healing is either impaired or insufficient, such as fracture non-union, osteoporosis …
[HTML][HTML] Strategies for cancer gene-delivery improvement by non-viral vectors
ML Santana-Armas, CT de Ilarduya - International journal of pharmaceutics, 2021 - Elsevier
Lack of selectivity together with severe side effects in conventional cancer treatment have
afforded the development of new strategies based on gene therapy. Nowadays, gene …
afforded the development of new strategies based on gene therapy. Nowadays, gene …
Ligand size and conformation affect the behavior of nanoparticles coated with in vitro and in vivo protein corona
Protein corona is immediately established on the surface of nanoparticles upon their
introduction into biological milieu. Several studies have shown that the targeting efficiency of …
introduction into biological milieu. Several studies have shown that the targeting efficiency of …
Comparison of transfection efficiency of nonviral gene transfer reagents
S Yamano, J Dai, AM Moursi - Molecular biotechnology, 2010 - Springer
This study compared six commercially available reagents (Arrest-In, ExpressFect, FuGENE
HD, jetPEI, Lipofectamine 2000, and SuperFect) for gene transfection. We examined the …
HD, jetPEI, Lipofectamine 2000, and SuperFect) for gene transfection. We examined the …
Non-viral gene delivery methods for bone and joints
B Gantenbein, S Tang, J Guerrero… - … in Bioengineering and …, 2020 - frontiersin.org
Viral carrier transport efficiency of gene delivery is high, depending on the type of vector.
However, viral delivery poses significant safety concerns such as inefficient/unpredictable …
However, viral delivery poses significant safety concerns such as inefficient/unpredictable …
Properties, engineering and applications of lipid-based nanoparticle drug-delivery systems: current research and advances
J Buse, A El-Aneed - Nanomedicine, 2010 - Taylor & Francis
Lipid-based drug-delivery systems have evolved from micro-to nano-scale, enhancing the
efficacy and therapeutic applications of these delivery systems. Production of lipid-based …
efficacy and therapeutic applications of these delivery systems. Production of lipid-based …