Circadian clocks and breast cancer

V Blakeman, JL Williams, QJ Meng, CH Streuli - Breast Cancer Research, 2016 - Springer
Circadian clocks respond to environmental time cues to coordinate 24-hour oscillations in
almost every tissue of the body. In the breast, circadian clocks regulate the rhythmic …

Circadian rhythms and reproduction

MJ Boden, DJ Kennaway - Reproduction, 2006 - rep.bioscientifica.com
There is a growing recognition that the circadian timing system, in particular recently
discovered clock genes, plays a major role in a wide range of physiological systems …

The clock gene Per2 links the circadian system to the estrogen receptor

S Gery, RK Virk, K Chumakov, A Yu, HP Koeffler - Oncogene, 2007 - nature.com
Circadian rhythms regulate diverse physiological processes including homeostatic functions
of steroid hormones and their receptors. Estrogen receptor-α (ERα) is essential for normal …

Gene expression in the human mammary epithelium during lactation: the milk fat globule transcriptome

PD Maningat, P Sen, M Rijnkels… - Physiological …, 2009 - journals.physiology.org
The molecular physiology underlying human milk production is largely unknown because of
limitations in obtaining tissue samples. Determining gene expression in normal lactating …

Altered circadian rhythms and breast cancer: from the human to the molecular level

HH Lin, ME Farkas - Frontiers in endocrinology, 2018 - frontiersin.org
Circadian clocks are fundamental, time-tracking systems that allow organisms to adapt to the
appropriate time of day and drive many physiological and cellular processes. Altered …

Circadian clock and breast cancer: a molecular link

S Saha, P Sassone-Corsi - Cell Cycle, 2007 - Taylor & Francis
The circadian clock controls a large array of behavioral and physiological systems of
fundamental importance to most organisms. Consequently, abnormal functioning of the …

Deregulated expression of the Per1 and Per2 in human gliomas

H Xia, Z Niu, H Ma, S Cao, S Hao, Z Liu… - Canadian journal of …, 2010 - cambridge.org
Background: Growing evidence shows that the deregulation of the circadian clock plays an
important role in the development of malignant tumors, including gliomas. However, the …

Working against our endogenous circadian clock: Breast cancer and electric lighting in the modern world

RG Stevens - Mutation Research/Genetic Toxicology and …, 2009 - Elsevier
Breast cancer incidence increases rapidly as societies industrialize. Many changes occur
during the industrialization process, one of which is a dramatic alteration in the lighted …

Expression levels of estrogen receptor β are modulated by components of the molecular clock

W Cai, J Rambaud, M Teboul, I Masse… - … and cellular biology, 2008 - Am Soc Microbiol
Circadian regulation of gene expression plays a major role in health and disease. The
precise role of the circadian system remains to be clarified, but it is known that circadian …

Health consequences of shift work and implications for structural design

MG Figueiro, RD White - Journal of Perinatology, 2013 - nature.com
The objective of the study was to perform a literature review on the health consequences of
working rotating shifts and implications for structural design. A literature search was …