Neuronal events are regulated by the integration of several complex signaling networks in
which G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) are …

Increasing evidence has been accumulating about the role of stress as an important
challenge to the onset and progression of Alzheimer's disease (AD). The hippocampus, one …

The differentiation of neural progenitors is a complex process that integrates different signals
to drive transcriptional changes, which mediate metabolic, electrophysiological, and …

Neuroblasts exist within the human subependymal zone (SEZ); however, it is debated to
what extent neurogenesis changes during normal aging. It is also unknown how precursor …

In the brains of adult vertebrates, including humans, neurogenesis occurs in restricted
niches where it maintains cellular turnover and cognitive plasticity. In virtually all species …

Background Recently, it was demonstrated that G-protein-coupled receptors (GPCRs) can
transactivate tyrosine kinase receptors in absence of their ligands. In this work, driven by the …

FGF2 is considered a key factor in the generation of oligodendrocytes (OLs) derived from
neural stem cells (NSCs) located within the subventricular zone (SVZ). Here, we have …

Rationale In depressive disorders, one of the mechanisms proposed for antidepressant
drugs is the enhancement of synaptic plasticity in the hippocampus and cerebral cortex …

Infrasound, a kind of ambient noise, can cause severe disorders to various human organs,
specially to central nervous system (CNS). Our previous studies have shown that infrasound …

In our recent study was shown a significant recovery of damaged skeletal muscle of mice
with X-linked muscular dystrophy (mdx) following low-intensity endurance exercise …