[HTML][HTML] Novel insights into ferroptosis: Implications for age-related diseases

RP Zhou, Y Chen, X Wei, B Yu, ZG Xiong, C Lu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rapid increase in aging populations is an urgent problem because older adults are more
likely to suffer from disabilities and age-related diseases (ARDs), burdening healthcare …

Antioxidants-related superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione-S-transferase (GST), and nitric oxide synthase (NOS) …

AMT Gusti, SY Qusti, EM Alshammari, EA Toraih… - Antioxidants, 2021 - mdpi.com
Oxidative stress and antioxidants play an important role in obesity etiopathology. Genetic
variants, including single nucleotide polymorphisms (SNPs) of the antioxidant-related …

Diabetic neuropathy in children and youth: new and emerging risk factors

G Akinci, MG Savelieff, G Gallagher… - Pediatric …, 2021 - Wiley Online Library
Pediatric neuropathy attributed to metabolic dysfunction is a well‐known complication in
children and youth with type 1 diabetes. Moreover, the rise of obesity and in particular of …

Glutathione S-Transferase (GSTT1 rs17856199) and Nitric Oxide Synthase (NOS2 rs2297518) Genotype Combination as Potential Oxidative Stress-Related …

AMT Gusti, SY Qusti, SM Bahijri, EA Toraih… - Diabetes, Metabolic …, 2021 - Taylor & Francis
Background Deregulation of the antioxidant enzymes was implicated in pathogenesis and
complications of type 2 diabetes mellitus (T2DM). The data relate the genetic variants of …

Current understanding of human polymorphism in selenoprotein genes: a review of its significance as a risk biomarker

RR Ferreira, RV Carvalho, LL Coelho… - International journal of …, 2024 - mdpi.com
Selenium has been proven to influence several biological functions, showing to be an
essential micronutrient. The functional studies demonstrated the benefits of a balanced …

Proteomics of high-density lipoprotein subfractions and subclinical atherosclerosis in type 1 diabetes mellitus: a case–control study

MTK Toyoshima, MFM Santana, ARM Silva… - Diabetology & Metabolic …, 2023 - Springer
Background Subclinical atherosclerosis is frequently observed in type 1 diabetes (T1D)
although the mechanisms and markers involved in the evolution to established …

Rs4862705 in the melatonin receptor 1A gene is associated with renal function decline in type 1 diabetes individuals

G Daher, DP Santos-Bezerra, AM Cavaleiro… - Frontiers in …, 2024 - frontiersin.org
Aim The pathogenesis of chronic diabetes complications has oxidative stress as one of the
major elements, and single-nucleotide polymorphisms (SNPs) in genes belonging to …

[HTML][HTML] Effect of fluorofenidone against paraquat-induced pulmonary fibrosis based on metabolomics and network pharmacology

F Jiang, T Wang, S Li, Y Jiang, Z Chen… - Medical Science Monitor …, 2021 - ncbi.nlm.nih.gov
Effect of Fluorofenidone Against Paraquat-Induced Pulmonary Fibrosis Based on Metabolomics
and Network Pharmacology - PMC Back to Top Skip to main content NIH NLM Logo Access …

Allelic variations in genes belonging to glutathione system increase proliferative retinopathy risk in type 1 diabetes individuals

RV Perez, CG Machado, DP Santos-Bezerra… - Gene, 2019 - Elsevier
Aims Given the participation of oxidative stress in the pathogenesis of diabetic
complications, we evaluated, in type 1 diabetes (T1D) individuals, the association between …

A Genotype–Phenotype Analysis of Glutathione Peroxidase 4 in Human Atrial Myocardium and Its Association with Postoperative Atrial Fibrillation

IA Berdaweel, AA Hart, AJ Jatis, N Karlan, SA Akhter… - Antioxidants, 2022 - mdpi.com
Heterogeneity in the incidence of postoperative atrial fibrillation (POAF) following heart
surgery implies that underlying genetic and/or physiological factors impart a higher risk of …